CAS 33025-60-4

1-(3-Hydroxy-1H-indol-1-yl)ethanone

Description:

1-(3-Hydroxy-1H-indol-1-yl)ethanone, also known as 3-Hydroxyindole-1-acetone, is an organic compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance features a hydroxyl group (-OH) at the 3-position of the indole ring and an acetyl group (-C(=O)CH3) attached to the nitrogen atom of the indole. It is typically a solid at room temperature and is soluble in polar solvents due to the presence of the hydroxyl group, which can engage in hydrogen bonding. The compound may exhibit biological activity, potentially influencing various biochemical pathways, making it of interest in medicinal chemistry and research. Its properties, such as melting point, boiling point, and reactivity, can vary based on environmental conditions and the presence of other substances. As with many indole derivatives, it may also display fluorescence, which can be useful in analytical applications.

Formula: C₁₀H₉NO₂

InChI: InChI=1S/C10H9NO2/c1-7(12)11-6-10(13)8-4-2-3-5-9(8)11/h2-6,13H,1H3

InChI key: InChIKey=NNJXIAOPPYUVAX-UHFFFAOYSA-N

SMILES: C(C)(=O)N1C=2C(C(O)=C1)=CC=CC2

Synonyms:

• 1-(3-Hydroxyindol-1-yl)ethanone
• 1-(3-hydroxy-1H-indol-1-yl)ethanone
• 1-Acetyl-3-hydroxyindole
• 1-Acetylindoxyl
• 1H-Indol-3-ol, 1-acetyl-
• Ethanone, 1-(3-hydroxy-1H-indol-1-yl)-
• Indoxyl, 1-acetyl-
• N-Acetylindol-3-ol

N-Acetyl-3-hydroxyindole

CAS: 33025-60-4

Formula: C₁₀H₉NO₂

Color and Shape: Solid

Molecular weight: 175.1840

Ref: IN-DA00BXOE

1-Acetyl-3-hydroxyindole

CAS: 33025-60-4

1-Acetyl-3-hydroxyindole

Purity: 95%

Color and Shape: Off-White To Yellow Solid

Molecular weight: 175.18g/mol

Ref: 54-OR928060

N-Acetyl-3-hydroxyindole

Controlled Product

CAS: 33025-60-4

Formula: C₁₀H₉NO₂

Color and Shape: Neat

Molecular weight: 175.18

Ref: TR-A178950

N-Acetyl-3-hydroxyindole

CAS: 33025-60-4

N-Acetyl-3-hydroxyindole is a colorless liquid that inhibits the activity of enzymes such as butyric acid, active methylene, and acyl halides. It is also used to inhibit the enzyme eosinophil peroxidase in clinical tests. N-Acetyl-3-hydroxyindole has been shown to be an efficient method for high-throughput analysis of enzymatic reactions. This chemical can be immobilized on porous supports and used to measure enzyme activities. N-Acetyl-3-hydroxyindole has been shown to have therapeutic effects in clinical data with a potent inhibitor of eosinophil peroxidase.

Formula: C₁₀H₉NO₂

Purity: Min. 95%

Color and Shape: Orange Powder

Molecular weight: 175.18 g/mol

Ref: 3D-FA17072

N-Acetyl-3-hydroxyindole

CAS: 33025-60-4

N-Acetyl-3-hydroxyindole is a chemical compound that can be used as a building block for other organic compounds. It is an intermediate in the synthesis of 3-amino-2,4,6-trichloropyrimidine, which is used in the synthesis of some pharmaceuticals and pesticides. N-Acetyl-3-hydroxyindole has been shown to react with thiourea to yield 2-(3,4-dihydroxyphenyl)acetic acid. It also reacts with hydroxylamine to produce 2-(aminooxymethyl)pyrrolidinone. N-Acetyl-3-hydroxyindole has been shown to have antioxidant properties, which may be due to its ability to reduce lipid peroxidation and scavenge reactive oxygen species.

Formula: C₁₀H₉NO₂

Purity: Min. 98.0 Area-%

Molecular weight: 175.19 g/mol

Ref: 3D-A-1290

1-Acetyl-3-indoxyl-d4

Controlled Product

CAS: 33025-60-4

Applications Auxin like molecule, used in the preparation of peptidomimetics.
References Ferro, N. et al.: J. Chem. Inf. Model., 46, 1751 (2006); Le D. et al.: Bioorg. Med. Chem. Lett., 6, 1983 (1996)

Formula: C₁₀D₄H₅NO₂

Color and Shape: Neat

Molecular weight: 179.209

Ref: TR-A178952