CAS 3303-84-2

BOC-β-alanine

Description:

BOC-β-alanine, also known as tert-butoxycarbonyl-β-alanine, is an amino acid derivative characterized by the presence of a tert-butoxycarbonyl (BOC) protecting group attached to the amino group of β-alanine. This compound is typically used in peptide synthesis and as a building block in organic chemistry due to its ability to protect the amine functionality during various reactions. BOC-β-alanine is a white to off-white solid that is soluble in organic solvents such as dichloromethane and dimethylformamide, but less soluble in water. Its molecular structure includes a carboxylic acid group, an amino group, and a β-carbon, which contributes to its classification as a β-amino acid. The BOC group can be removed under acidic conditions, allowing for the regeneration of the free amino group for further chemical transformations. BOC-β-alanine is valued for its stability and ease of handling, making it a useful reagent in synthetic organic chemistry and biochemistry applications.

Formula: C₈H₁₅NO₄

InChI: InChI=1S/C8H15NO4/c1-8(2,3)13-7(12)9-5-4-6(10)11/h4-5H2,1-3H3,(H,9,12)(H,10,11)

InChI key: InChIKey=WCFJUSRQHZPVKY-UHFFFAOYSA-N

SMILES: C(OC(C)(C)C)(NCCC(O)=O)=O

Synonyms:

• 3-(tert-Butoxycarbonylamino)propanoic acid
• 3-(tert-Butoxycarbonylamino)propionic acid
• 3-[(2-Methylpropan-2-yl)oxycarbonylamino]propanoic acid
• 3-[(Tert-Butoxycarbonyl)Amino]Propanoate
• 3-[N-(tert-Butoxycarbonyl)amino]propionic acid
• BOC-3-aminopropanoic acid
• BOC-beta-Alanine
• Boc-3-aminopropionic acid
• Boc-b-alanine
• Boc-beta-Ala
• Boc-beta-Ala-OH
• Boc-ß -Ala-OH
• Boc-β-Ala-OH
• Butoxycarbonylalanine
• N-(t-Butoxycarbonyl)-β-alanine
• N-(tert-Butoxycarbonyl)-3-aminopropionic acid
• N-(tert-Butyloxycarbonyl)-β-alanine
• N-Boc-3-aminopropanoic acid
• N-Boc-β-alanine
• N-T-boc-B-alanine crystalline
• N-[(1,1-Dimethylethoxy)carbonyl]-β-alanine
• N-[(t-Butyloxy)carbonyl]-β-alanine
• N-tert-Butoxycarbonyl-3-aminopropanoic acid
• N-tert-Butoxycarbonyl-β-alanine
• β-Alanine, N-[(1,1-dimethylethoxy)carbonyl]-
• β-Alanine, N-carboxy-, N-tert-butyl ester
• N-(tert-Butoxycarbonyl)-beta-alanine

3-tert-Butoxycarbonylaminopropionic acid

CAS: 3303-84-2

Formula: C₈H₁₅NO₄

Purity: 97%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 189.211

Ref: 10-F019572

N-Boc-β-alanine, 99%

CAS: 3303-84-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₅NO₄

Purity: 99%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 189.21

Ref: 02-B22522

Boc-β-Ala-OH

CAS: 3303-84-2

Formula: C₈H₁₅NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 189.2090

Ref: IN-DA003STN

Boc-β-Ala-OH

CAS: 3303-84-2

Formula: C₈H₁₅NO₄

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 189.21

Ref: 7W-GM2445

N-(tert-Butoxycarbonyl)-β-alanine

CAS: 3303-84-2

Formula: C₈H₁₅NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 189.21

Ref: 3B-B2176

β-Alanine, N-BOC protected

CAS: 3303-84-2

β-Alanine, N-BOC protected

Formula: C₈H₁₅NO₄

Purity: 98%

Color and Shape: white to light yellow solid

Molecular weight: 189.21g/mol

Ref: 54-OR52389

Boc-ß-Ala-OH

CAS: 3303-84-2

Boc-ß-Ala-OH is an amino acid that inhibits the activity of gamma-aminobutyric acid (GABA) receptors. It has been shown to bind to the GABA receptor and block its activation by GABA. Boc-ß-Ala-OH is used as a building block for peptide synthesis, where it can be coupled with other amino acids to form a desired peptide sequence. This amino acid also possesses intramolecular hydrogen bonding interactions, which have been found to contribute to its inhibitory properties. Boc-ß-Ala-OH has a phase transition temperature of 104°C and is soluble in water below this point.

Formula: C₈H₁₅NO

Purity: Min. 95%

Molecular weight: 189.21 g/mol

Ref: 3D-BBA-2131

BOC-β-alanine

CAS: 3303-84-2

BOC-β-alanine is a trifluoroacetic acid derivative that is activated with carbodiimides to form the ester hydrochloride. It has been shown to have anticancer activity in vitro and in vivo. BOC-β-alanine inhibits the synthesis of polypeptides by binding to the carboxyl group on the amino acid, thereby preventing protein formation. This compound also has an inhibitory effect on cell proliferation of 3T3-L1 preadipocytes in culture, which may be due to its ability to deplete fibrinogen from cells and inhibit activation of adenyl cyclase.

Formula: C₈H₁₅NO₄

Color and Shape: White Powder

Molecular weight: 189.21 g/mol

Ref: 3D-FB36817

Boc-​β-​Ala-​OH

Controlled Product

CAS: 3303-84-2

Applications Boc-​β-​Ala-​OH is a reagent used in the synthesis of quinazolines as platelet aggregation inhibitors and ligands of integrin.
References Krysko, A. et al.: Bioorg. Med. Chem. Lett., 26, 1839 (2016);

Formula: C₈H₁₅NO₄

Color and Shape: Neat

Molecular weight: 189.21

Ref: TR-B619515