CAS 330786-24-8

5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylamine

Description:

5-(4-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine, with the CAS number 330786-24-8, is a chemical compound that belongs to the class of pyrrolopyrimidines. This compound features a pyrrolo[2,3-d]pyrimidine core structure, which is characterized by a fused bicyclic system that includes both pyrrole and pyrimidine rings. The presence of a phenoxyphenyl substituent enhances its potential for various biological activities, making it of interest in medicinal chemistry. The amine functional group in its structure suggests potential for hydrogen bonding, which can influence its solubility and reactivity. Typically, compounds like this may exhibit properties such as moderate to high lipophilicity, depending on the substituents, and may interact with biological targets, potentially serving as inhibitors or modulators in various biochemical pathways. Its specific characteristics, including melting point, solubility, and biological activity, would require empirical data for precise evaluation.

Formula: C₁₇H₁₃N₅O

Synonyms:

• 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• 4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidine
• 5-(4-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• Ibrutinib deacryloylpiperidine
• 5-(4-phenoxyphenyl)-7H-pyrrolo[2
• 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine
• 3-(4-phenoxyphenyl)-2H-pyrazolo[3,4-d]pyrimidin-4-amine
• 5- (4-phenoxyphenyl) -7H-pyrrolio [2,3-d] pyrimidin-4-ylamine
• 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylamine (N-2)
• 3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidine
• Ibrutinib N-Despiperidinyl Impurity
• Ibrutinib intermeidate N-2
• 3-(4-Phenoxypheny)- 1Hpyrazolo[3.4-dlpyrimidin-4-amine
• Ibrutinib deacryloylpiperidine (Ibrutinib Impurity)
• 3-(4-Phenoxyphenyl)pyrazolo[3,4-D]pyrimidin-4-amine
• Ibrutinib Impurity 8
• Ibrutinib intermediates N-2
• Ibrutinib Impurity 46
• Ibrutinib impurity 3/
• 5-(4-PHENOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINE/3-(4-PHENOXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
• Ibrutinib intermediate 2
• 3-(4-Phenoxyphenyl)-1H-pyrazoleand[3,4-d]pyrimidine-4-amine
• 2) 3-(4-PHENOXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE
• 3-(4- phenoxyphenyl) -1H- pyrazolo [3,4-d] pyrimidine -4- amine
• PCI-32765 (IBRUTINIB) INTERMEDIATE(N-2)
• ibrutinib N-2
• 3-(4-phenoxyphenyl)-1 H- pyrazolium [3,4- D] pyrimidine-4-amine
• -(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine
• 1H-Pyrazolo[3,4-d]pyriMidin-4-aMine, 3-(4-phenoxyphenyl)-
• 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine/Ibrutinib impurity
• Ibrutinib INT1
• IbrutinibintermeidChemicalbookateN-2
• 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine ISO 9001：2015 REACH
• 5-(3-Phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 3-d]pyriMidin-4-ylaMine
• 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-y
• Ilutinib impurity 8
• 10-Morpholineethanamine,N-(cyclohexylcarbonimidoyl)-

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

CAS: 330786-24-8

Formula: C₁₇H₁₃N₅O

Purity: 98%

Color and Shape: Solid

Molecular weight: 303.3180

Ref: IN-DA003KOV

Ibrutinib deacryloylpiperidine

CAS: 330786-24-8

Ibrutinib deacryloylpiperidine

Purity: ≥98%

Molecular weight: 303.32g/mol

Ref: 54-BUP17973

Ibrutinib Impurity 8

CAS: 330786-24-8

Formula: C₁₇H₁₃N₅O

Color and Shape: Gray Solid

Molecular weight: 303.33

Ref: 4Z-I-061011

5-(4-Phenoxyphenyl)-7H-Pyrrolo[2,3-d]Pyrimidin-4-Ylamine

CAS: 330786-24-8

5-(4-Phenoxyphenyl)-7H-Pyrrolo[2,3-d]Pyrimidin-4-Ylamine

Purity: 98%

Molecular weight: 303.31802g/mol

Ref: 54-OR1011714

3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4 d)pyrimidin-4-amine

CAS: 330786-24-8

Color and Shape: Neat

Ref: 86-MM3746.03

Ibrutinib deacryloylpiperidine

CAS: 330786-24-8

Ibrutinib deacryloylpiperidine (IBT4A) is a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor with an IC50 of 0.5 nM.

Formula: C₁₇H₁₃N₅O

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 303.32

Ref: TM-T8636

3-(4-PHENOXYPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE

CAS: 330786-24-8

Purity: 97%

Molecular weight: 303.32501220703125

Ref: 10-F857010

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

CAS: 330786-24-8

Intermediate in the synthesis of ibrutinib

Formula: C₁₇H₁₃N₅O

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 303.32 g/mol

Ref: 3D-FP59832

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Controlled Product

CAS: 330786-24-8

Applications 3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a useful synthetic intermediate in the synthesis of Ibrutinib (I124970); a highly selective Bruton’s tyrosine kinase (BTK) irreversible inhibitor.
References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011); Li, X., et al.: J. Med. Chem., 58, 9625 (2015)

Formula: C₁₇H₁₃N₅O

Color and Shape: Light Brown To Brown

Molecular weight: 303.32

Ref: TR-P301390