CAS 330942-05-7

Betrixaban

Description:

Betrixaban is an oral anticoagulant that belongs to the class of direct factor Xa inhibitors. It is primarily used for the prevention of venous thromboembolism in patients undergoing elective hip or knee replacement surgery. The substance works by selectively inhibiting factor Xa, an essential enzyme in the coagulation cascade, thereby reducing thrombin generation and preventing clot formation. Betrixaban is characterized by its high bioavailability and a relatively long half-life, allowing for once-daily dosing. Its chemical structure includes a unique bicyclic core that contributes to its potency and specificity for factor Xa. The pharmacokinetics of Betrixaban are influenced by factors such as age, renal function, and concomitant medications, which can affect its metabolism and clearance. As with other anticoagulants, monitoring for bleeding risks is crucial during its use. Overall, Betrixaban represents a significant advancement in anticoagulant therapy, providing an effective option for thromboprophylaxis with a favorable safety profile.

Formula: C₂₃H₂₂ClN₅O₃

InChI: InChI=1S/C23H22ClN5O3/c1-29(2)21(25)14-4-6-15(7-5-14)22(30)27-19-10-9-17(32-3)12-18(19)23(31)28-20-11-8-16(24)13-26-20/h4-13,25H,1-3H3,(H,27,30)(H,26,28,31)

InChI key: InChIKey=XHOLNRLADUSQLD-UHFFFAOYSA-N

SMILES: N(C(=O)C1=CC=C(C(N(C)C)=N)C=C1)C2=C(C(NC3=CC=C(Cl)C=N3)=O)C=C(OC)C=C2

Synonyms:

• Benzamide, N-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy-
• Betrixaban
• Bevyxxa
• N-(5-Chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxybenzamide
• Prt 054021

Betrixaban

CAS: 330942-05-7

Formula: C₂₃H₂₂ClN₅O₃

Purity: >95.0%(HPLC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 451.91

Ref: 3B-B6398

Betrixaban

CAS: 330942-05-7

Formula: C₂₃H₂₂ClN₅O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 451.9055

Ref: IN-DA00C6EX

Betrixaban

CAS: 330942-05-7

Ref: 7W-GK7684

N-(5-Chloropyridin-2-Yl)-2-(4-(N,N-Dimethylcarbamimidoyl)Benzamido)-5-Methoxybenzamide

CAS: 330942-05-7

N-(5-Chloropyridin-2-Yl)-2-(4-(N,N-Dimethylcarbamimidoyl)Benzamido)-5-Methoxybenzamide

Purity: 98%

Molecular weight: 451.91g/mol

Ref: 54-OR1026359

Betrixaban

CAS: 330942-05-7

Betrixaban

Purity: ≥98%

Molecular weight: 451.91g/mol

Ref: 54-BUP13035

Betrixaban-d4

CAS: 330942-05-7

Formula: C₂₃H₁₈D₄ClN₅O₃

Molecular weight: 455.94

Ref: 4Z-B-187009

Betrixaban

CAS: 330942-05-7

Formula: C₂₃H₂₂ClN₅O₃

Molecular weight: 451.91

Ref: 4Z-B-187001

Betrixaban

Controlled Product

CAS: 330942-05-7

Applications Betrixaban is a novel anticoagulant. An oral direct inhibitor of factor Xa (FXa) for use in the prevention of venous thromboembolism (VTE).
References Turpie, A.G.G. et al.: Thromb. Haemost., 101, 68 (2009); Gomez-Outes, A. et al.: Curr. Vasc. Pharmacol., 7, 309 (2009);

Formula: C₂₃H₂₂ClN₅O₃

Color and Shape: Light Yellow

Molecular weight: 451.91

Ref: TR-B329500

Betrixaban

CAS: 330942-05-7

Inhibitor of factor Xa

Formula: C₂₃H₂₂ClN₅O₃

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 451.91 g/mol

Ref: 3D-FC18577

Betrixaban - Bio-X ™

CAS: 330942-05-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₂₃H₂₂ClN₅O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 451.91 g/mol

Ref: 3D-BB167058

Betrixaban

CAS: 330942-05-7

Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.

Formula: C₂₃H₂₂ClN₅O₃

Purity: 99.33%

Color and Shape: Solid

Molecular weight: 451.91

Ref: TM-T4341

Betrixaban-d6

Controlled Product

CAS: 330942-05-7

Formula: C₂₃D₆H₁₆ClN₅O₃

Color and Shape: Neat

Molecular weight: 457.942

Ref: TR-B329503