CAS 3313-27-7

trans-Thiothixene

Description:

Trans-Thiothixene is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of compounds and is characterized by its ability to antagonize dopamine receptors, particularly D2 receptors, which plays a crucial role in its therapeutic effects. The chemical structure of trans-Thiothixene includes a thioxanthene core, which contributes to its pharmacological properties. It is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. The substance exhibits a range of side effects, including sedation, extrapyramidal symptoms, and potential metabolic changes, which necessitate careful monitoring during treatment. Additionally, trans-Thiothixene has a relatively long half-life, allowing for less frequent dosing compared to some other antipsychotics. Its efficacy and safety profile make it a valuable option in the management of severe mental health conditions, although individual responses may vary significantly. As with all medications, it is essential to use trans-Thiothixene under the guidance of a qualified healthcare professional.

Formula: C₂₃H₂₉N₃O₂S₂

InChI: InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8+

InChI key: InChIKey=GFBKORZTTCHDGY-UFWORHAWSA-N

SMILES: C(\CCN1CCN(C)CC1)=C\2/C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Synonyms:

• (9E)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• (E)-Thiothixene
• 9H-Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, (E)-
• P 4657A
• Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, (E)-
• Thioxanthene-2-sulfonamide,N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, (E)- (8CI)
• trans-Thiothixene
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-, (9E)-

(E)-Thiothixene

CAS: 3313-27-7

Sulfonamides, nesoi

Formula: C₂₃H₂₉N₃O₂S₂

Color and Shape: White Off-White Powder

Molecular weight: 443.17012

Ref: 45-1666006

trans-Thiothixene

CAS: 3313-27-7

Formula: C₂₃H₂₉N₃O₂S₂

Molecular weight: 443.62

Ref: 4Z-T-228003

(E)-Thiothixene

Controlled Product

CAS: 3313-27-7

Applications (E)-Thiothixene is an antipsychotic agent used in the treatment of psychological disorders.
References Andorn, A. et al.: Brain Res., 971, 66 (2003); Seeman, P. et al.: Mol. Pharmacol. 28, 391 (1985);

Formula: C₂₃H₂₉N₃O₂S₂

Color and Shape: Neat

Molecular weight: 443.63

Ref: TR-T375280

(E)-Thiothixene

CAS: 3313-27-7

Formula: C₂₃H₂₉N₃O₂S₂

Molecular weight: 443.62

Ref: ST-EA-CP-T150003