CAS 331752-47-7

Cyclohexanecarboxamide,4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, hydrochloride, hydrate (1:2:1), trans-

Description:

Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, hydrochloride, hydrate (1:2:1), trans- is a chemical compound characterized by its complex structure, which includes a cyclohexane ring, an amide functional group, and a pyridine moiety. This compound is typically encountered as a hydrochloride salt, indicating it is soluble in water and may exhibit different properties compared to its free base form. The presence of the aminoethyl group suggests potential biological activity, possibly interacting with various receptors or enzymes. The trans configuration indicates specific stereochemistry, which can influence the compound's pharmacological properties. As a hydrate, it contains water molecules in its crystalline structure, which can affect its stability and solubility. This compound may be of interest in medicinal chemistry and pharmacology, particularly for its potential therapeutic applications. However, detailed studies on its biological activity, toxicity, and pharmacokinetics would be necessary to fully understand its characteristics and potential uses.

Formula: C₁₄H₂₁N₃O・2ClH・H₂O

Synonyms:

• Cyclohexanecarboxamide,4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, dihydrochloride, monohydrate, trans-(9CI)

(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-pyridyl)cyclohexanecarboxamide Dihydrochloride Monohydrate

CAS: 331752-47-7

Formula: C₁₄H₂₅Cl₂N₃O₂

Molecular weight: 338.2732

Ref: IN-DA00C9IU

Y-27632 HCl hydrate

CAS: 331752-47-7

Y-27632 HCl hydrate is an orally effective, ATP-competitive ROCK1/ROCK2 inhibitor (Ki=220 nM/300 nM) that inhibits caspase-3 and suppresses stem cell apoptosis.

Formula: C₁₄H₂₅Cl₂N₃O₂

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 338.27

Ref: TM-T69429

Y-27632-d4 Dihydrochloride Hydrate

Controlled Product

CAS: 1316891-98-1, 331752-47-7

Applications A labelled Rho kinase inhibitor (ROCK) for the treatment of ischemia-reperfusion disorders.
References Hirose, M., et al.: J. Cell. Biol., 141, 1625 (1998), Maekawa, M., et al.: Science, 285, 895 (1999), Ye, X., et al.: Jpn. J. Pharmacol., 83, 161 (2000), Chitaley, et al.: Nat. Med., 7, 119 (2001), Watanabe, K., et al.: Nature Biotech., 25, 681 (2007),

Formula: C₁₄H₂₁D₄Cl₂N₃O₂

Color and Shape: Grey

Molecular weight: 342.3

Ref: TR-Y100502