CAS 331943-04-5

Benzenesulfonamide,4-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-

Description:

Benzenesulfonamide, 4-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]- is a chemical compound characterized by its sulfonamide functional group, which is known for its antibacterial properties. This compound features a pyrazole ring substituted with a trifluoromethyl group and a 4-methylphenyl moiety, contributing to its unique chemical behavior and potential biological activity. The presence of the trifluoromethyl group enhances lipophilicity and can influence the compound's pharmacokinetic properties. The sulfonamide group is typically associated with various therapeutic applications, including use as diuretics and in the treatment of bacterial infections. The compound's structure suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its solubility, stability, and reactivity can vary based on environmental conditions and the presence of other functional groups. Overall, this compound exemplifies the complexity and diversity of sulfonamide derivatives in pharmaceutical research.

Formula: C₁₇H₁₄F₃N₃O₂S

Synonyms:

• Celecoxib EP Impurity B(USP RC B)
• Celecoxib EP Impurity B (CelecoxibregioIsomer)
• Celecoxib EP Impurity B/ Celecoxib Related Compound B
• Celecoxib EP Imp B
• N-De(4-sulfonamidophenyl)-Na€-(4-sulfonamidophenyl) Celecoxib
• Celecoxib Impurity 4（Celecoxib EP Impurity B）
• Celecoxib Impurity 4（EP Impurity B）
• Celecoxib impurity 2/Celecoxib EP Impurity B/4-[3-(4-Methylphenyl)-5-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide
• Celecoxib Related CoMpound B
• Isocelecoxib
• Celecoxib Related Compound B (10 mg) (4-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide)
• N-De(4-sulfonaMidophenyl)-N'-(4-sulfonaMidophenyl) Celecoxib
• Celebrex B
• Celecoxib-2
• benzenesulfonamide
• BenzenesulfonaMide, 4-[3-(4-Methylphenyl)-5-(trifluoroMethyl)-1H-pyrazol-1-yl]-
• 4-[3-(4-Methylphenyl)-5-(trifluoroMethyl)-1H-pyrazol-1-yl]benzenesulfonaMide

CELECOXIB IMPURITY B CRS

CAS: 331943-04-5

CELECOXIB IMPURITY B CRS

Ref: 41-Y0001447

Celecoxib Related Compound B (4-[3-(4-methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide)

CAS: 331943-04-5

Sulfonamides, nesoi

Formula: C₁₇H₁₄F₃N₃O₂S

Color and Shape: White Solid

Molecular weight: 381.07588

Ref: 45-1098526

Celecoxib EP Impurity B (Celecoxib USP Related Compound B, Celecoxib Regio Isomer)

CAS: 331943-04-5

Formula: C₁₇H₁₄F₃N₃O₂S

Color and Shape: Off-White Solid

Molecular weight: 381.37

Ref: 4Z-C-037

4-[3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide

CAS: 331943-04-5

Color and Shape: Neat

Ref: 86-MM0344.07

N-De(4-sulfonamidophenyl)-N’-(4-sulfonamidophenyl) Celecoxib

Controlled Product

CAS: 331943-04-5

Impurity Celecoxib EP Impurity B
Applications N-De(4-sulfonamidophenyl)-N’-(4-sulfonamidophenyl) Celecoxib (Celecoxib EP Impurity B) is an isomeric impurity of Celecoxib (C251000) with selective inhibitory activity against human cyclooxygenase-2. USP Celecoxib Related Compound B
References Talley, J.J. et al.: Actual. Chim. Therap., 25, 123 (1999); Rao, R. et al.: Anal. Sci., 22, 1257 (2006);

Formula: C₁₇H₁₄F₃N₃O₂S

Color and Shape: Neat

Molecular weight: 381.37

Ref: TR-D297915

Celecoxib EP Impurity B

CAS: 331943-04-5

Formula: C₁₇H₁₄F₃N₃O₂S

Molecular weight: 381.37

Ref: ST-EA-CP-C13002

N-De(4-sulfonamidophenyl)-N'-(4-sulfonamidophenyl) celecoxib

CAS: 331943-04-5

N-De(4-sulfonamidophenyl)-N'-(4-sulfonamidophenyl) celecoxib is an impurity of the drug celecoxib. It is a synthetic chemical compound that has been used in the synthesis of the drug celecoxib. N-De(4-sulfonamidophenyl)-N'-(4-sulfonamidophenyl) celecoxib is a crystalline solid with melting point at 136º C. It is soluble in chloroform, ethanol and acetone and insoluble in water. The chemical compound has been isolated by using a supercritical fluid chromatography technique and characterized by means of various analytical techniques such as fluid chromatography, crystallization, product yield, bulk drug, supercritical fluid chromatography, and chromatographic methods. This chemical compound has been found to contain contaminants such as metal ions (Zn2+, Ca2+, Mg2+) which can be

Formula: C₁₇H₁₄F₃N₃O₂S

Purity: Min. 95%

Molecular weight: 381.37 g/mol

Ref: 3D-FD20806