CAS 331948-99-3

2-((2-Phenoxyethyl)thio)-1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazole

CAS: 331948-99-3

2-((2-Phenoxyethyl)thio)-1-(2-(p-tolyloxy)ethyl)-1H-benzo[d]imidazole

Purity: 98%

Molecular weight: 404.54g/mol

Ref: 54-OR1067190

1-[2-(4-Methylphenoxy)ethyl]-2-[(2-phenoxyethyl)thio]-1H-benzimidazole

CAS: 331948-99-3

1-[2-(4-Methylphenoxy)ethyl]-2-[(2-phenoxyethyl)thio]-1H-benzimidazole (DETB) is a multidrug efflux pump inhibitor that is activated by hydroxyl group. It is a potential drug target for the treatment of bacterial infections, especially those caused by tetracycline resistant bacteria. DETB has been shown to inhibit the multidrug efflux pumps in human serum and in bacterial cells, which may be due to its ability to bind to fatty acids and p-hydroxybenzoic acid. DETB has been shown to have antimicrobial activity against gram negative bacteria such as Escherichia coli, Salmonella enterica and Pseudomonas aeruginosa. This compound also has the ability to inhibit the growth of gram positive bacteria such as Staphylococcus aureus.

Formula: C₂₄H₂₄N₂O₂S

Purity: Min. 95%

Molecular weight: 404.52 g/mol

Ref: 3D-GNA94899