CAS 331949-35-0

4,4-dimethyl-1-(3-nitrophenyl)-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-one

CAS: 331949-35-0

Formula: C₁₅H₁₆N₄O₃

Purity: 98%

Molecular weight: 300.3125

Ref: IN-DA01DADN

Nexinhib20

CAS: 331949-35-0

Nexinhib20

Purity: ≥98%

Molecular weight: 300.31g/mol

Ref: 54-BUP00751

Nexinhib 20

Controlled Product

CAS: 331949-35-0

Applications Nexinhib 20 is an inhibitor of Rab27a-JFC1 interaction, it inhibits the neutrophil exocytosis and inflammation
References Johnson, Jennifer. et al., J. BIOL. CHEM. 50, 25965-25982(2016);

Formula: C₁₅H₁₆N₄O₃

Color and Shape: Neat

Molecular weight: 300.312

Ref: TR-N204050

Nexinhib 20

CAS: 331949-35-0

Nexinhib 20 is a pro-inflammatory cytokine inhibitor that inhibits the production of pro-inflammatory cytokines, such as IL-1β and TNFα. It has been shown to be effective in reducing the growth of primary tumor cells and also reduces inflammation in diseases such as cancer, inflammatory bowel disease (IBD), and bowel diseases. Nexinhib 20 is not absorbed well when ingested orally due to its low bioavailability. It is also an acidic protein with a pI of 4.8.

Formula: C₁₅H₁₆N₄O₃

Purity: Min. 95%

Molecular weight: 300.31 g/mol

Ref: 3D-GNA94935

Nexinhib20

CAS: 331949-35-0

Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.

Formula: C₁₅H₁₆N₄O₃

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 300.31

Ref: TM-T38384