CAS 332117-28-9

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide

Description:

The chemical substance known as 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide, with the CAS number 332117-28-9, is a complex organic compound that belongs to the class of purine derivatives. It features a purine core structure, which is characterized by a fused double-ring system containing nitrogen atoms. The presence of multiple functional groups, including amide and ketone functionalities, contributes to its potential biological activity. This compound may exhibit properties such as solubility in organic solvents, and its molecular structure suggests possible interactions with biological targets, making it of interest in pharmaceutical research. The presence of substituents like the 1-methylpropyl group on the phenyl ring may influence its lipophilicity and overall pharmacokinetic profile. As with many compounds in medicinal chemistry, its efficacy and safety would need to be evaluated through rigorous testing.

Formula: C₁₉H₂₃N₅O₃

Synonyms:

• CS-1651
• CheMbridge 5861528
• TCS 5861528;TCS-5861528;TCS5861528
• 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide
• 7H-Purine-7-acetamide, 1,2,3,6-tetrahydro-1,3-dimethyl-N-[4-(1-methylpropyl)phenyl]-2,6-dioxo-
• CHEMBRIDGE-5861528;TCS-5861528;TCS5861528
• TCS 5861528

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide

CAS: 332117-28-9

Formula: C₁₉H₂₃N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.4176

Ref: IN-DA00C6IQ

Chembridge-5861528

CAS: 332117-28-9

Chembridge-5861528

Purity: ≥98%

Molecular weight: 369.42g/mol

Ref: 54-BUP10530

Chembridge-5861528

CAS: 332117-28-9

Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM.

Formula: C₁₉H₂₃N₅O₃

Purity: 99.97%

Color and Shape: Solid

Molecular weight: 369.42

Ref: TM-T2711

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-[4-(1-methylpropyl)phenyl]acetamide

CAS: 332117-28-9

Purity: 98%

Molecular weight: 369.4249878

Ref: 10-F863474

Chembridge-5861528

Controlled Product

CAS: 332117-28-9

Chembridge-5861528 is an experimental drug that activates TRPA1 channels, which are cation channels in the peripheral nerve. It has been shown to induce pain and activate sensory neurons in animals with diabetic neuropathy and allergic symptoms. Chembridge-5861528 also inhibits pro-inflammatory cytokines, such as IL-1β, IL-6 and TNF-α, which are associated with pain. This drug has shown efficacy in clinical studies for the treatment of neuropathic pain.

Formula: C₁₉H₂₃N₅O₃

Purity: Min. 95%

Molecular weight: 369.42 g/mol

Ref: 3D-HNA11728