CAS 332374-42-2

2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzaldehyde

Description:

2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzaldehyde is an organic compound characterized by its complex structure, which includes a benzaldehyde moiety, an ethoxy group, and a sulfonamide linkage to a piperazine derivative. This compound typically exhibits properties such as moderate solubility in organic solvents and potential reactivity due to the presence of the aldehyde functional group, which can participate in various chemical reactions, including condensation and oxidation. The sulfonyl group enhances the compound's polarity and may influence its biological activity, making it of interest in medicinal chemistry. The piperazine ring contributes to the compound's pharmacological properties, often associated with neuroactive compounds. Overall, this substance may be explored for its potential applications in drug development, particularly in targeting specific biological pathways or receptors. As with many organic compounds, safety and handling precautions should be observed, given the potential for toxicity or reactivity.

Formula: C₁₄H₂₀N₂O₄S

InChI: InChI=1S/C14H20N2O4S/c1-3-20-14-5-4-13(10-12(14)11-17)21(18,19)16-8-6-15(2)7-9-16/h4-5,10-11H,3,6-9H2,1-2H3

InChI key: InChIKey=PZZJTXYBHOEFPL-UHFFFAOYSA-N

SMILES: S(=O)(=O)(C1=CC(C=O)=C(OCC)C=C1)N2CCN(C)CC2

Synonyms:

• Benzaldehyde, 2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]-
• 2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]benzaldehyde
• Piperazine, 1-[(4-ethoxy-3-formylphenyl)sulfonyl]-4-methyl-

Sildenafil Impurity 2

CAS: 332374-42-2

Formula: C₁₄H₂₀N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 312.39

Ref: 4Z-S-0690

2-Ethoxy-5-(4-methylpiperazine-1-sulfonyl)benzaldehyde (1-[(4-Ethoxy-3-formylphenyl)sulfonyl]-4-methylpiperazine)

Controlled Product

CAS: 332374-42-2

Formula: C₁₄H₂₀N₂O₄S

Color and Shape: Neat

Molecular weight: 312.38

Ref: 86-MM0254.21

2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl)]-benzaldehyde

Controlled Product

CAS: 332374-42-2

Applications 2-Ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl)]-benzaldehyde is an intermediate in the synthesis of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996), Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998),

Formula: C₁₄H₂₀N₂O₄S

Color and Shape: Neat

Molecular weight: 312.38

Ref: TR-E678355

Sildenafil Impurity 13

CAS: 332374-42-2

Formula: C₁₄H₂₀N₂O₄S

Molecular weight: 312.39

Ref: ST-EA-CP-S2047