CAS 33263-44-4

4-Chloro-3-pyridinesulfonyl chloride

Description:

4-Chloro-3-pyridinesulfonyl chloride is an organic compound characterized by its sulfonyl chloride functional group attached to a pyridine ring. It features a chlorine atom at the 4-position and a sulfonyl chloride group at the 3-position of the pyridine, which contributes to its reactivity and utility in organic synthesis. This compound is typically a solid at room temperature and is known for its ability to act as a sulfonating agent, making it valuable in the synthesis of various pharmaceuticals and agrochemicals. It is also used in the preparation of sulfonamide derivatives and other functionalized compounds. Due to the presence of the sulfonyl chloride group, it is reactive towards nucleophiles, which can lead to the formation of sulfonamides or other derivatives. Safety precautions are necessary when handling this compound, as it can be corrosive and may cause irritation to the skin and eyes. Proper storage in a cool, dry place away from moisture is recommended to maintain its stability.

Formula: C₅H₃Cl₂NO₂S

InChI: InChI=1S/C5H3Cl2NO2S/c6-4-1-2-8-3-5(4)11(7,9)10/h1-3H

InChI key: InChIKey=KCNWYJPUGJYMNO-UHFFFAOYSA-N

SMILES: S(Cl)(=O)(=O)C=1C(Cl)=CC=NC1

Synonyms:

• 3-Pyridinesulfonyl chloride, 4-chloro-
• 4-Chloro-3-pyridinesulfonyl chloride
• 4-Chloro-3-pyridinesulfonylchloride
• 4-Chloro-3-pyridinylsulfonyl chloride
• 4-Chloro-3-pyridylsulfonyl chloride
• 4-Chloro-3-pyridylsulfonylchloride

4-Chloro-3-pyridinesulfonyl chloride

CAS: 33263-44-4

Formula: C₅H₃Cl₂NO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 212.0538

Ref: IN-DA0037N1

4-Chloropyridine-3-sulfonyl chloride

CAS: 33263-44-4

4-Chloropyridine-3-sulfonyl chloride

Purity: 97%

Molecular weight: 212.05g/mol

Ref: 54-OR76518

Torasemide (Torsemide) Impurity 10

CAS: 33263-44-4

Formula: C₅H₃Cl₂NO₂S

Molecular weight: 212.04

Ref: 4Z-T-1120

4-Chloropyridine-3-sulfonyl chloride

CAS: 33263-44-4

Purity: 97%

Color and Shape: Solid

Molecular weight: 212.0399933

Ref: 10-F640636

4-chloropyridine-3-sulfonyl chloride

CAS: 33263-44-4

4-Chloropyridine-3-sulfonyl chloride is a thrombin inhibitor that has been discovered through the use of in vitro screening methods. It is a small molecule with lipophilic properties and oral bioavailability. This compound inhibits thrombin by binding to the active site of the enzyme, which prevents the formation of an enzyme-thrombin complex. The discovery was made using a pharmacophore-based approach and further modifications were made to improve its potency and increase its lipophilicity. This compound also exhibits an acceptable level of bioavailability in vivo, which may be due to its high solubility in water.

Formula: C₅H₃Cl₂NO₂S

Purity: Min. 95%

Molecular weight: 212.1 g/mol

Ref: 3D-IBA26344