CAS 33275-72-8

Erythromycin, 8,9-didehydro-9-deoxo-6,12-dideoxy-6,9-epoxy-

Description:

Erythromycin, 8,9-didehydro-9-deoxo-6,12-dideoxy-6,9-epoxy- is a derivative of erythromycin, a macrolide antibiotic known for its effectiveness against a variety of bacterial infections. This specific compound features structural modifications that enhance its pharmacological properties. It typically exhibits a broad spectrum of antibacterial activity, particularly against Gram-positive bacteria and some Gram-negative organisms. The presence of the epoxy group and the didehydro modifications can influence its stability, solubility, and overall bioactivity. Erythromycin derivatives are often utilized in clinical settings for patients allergic to penicillin or when penicillin is ineffective. The compound's mechanism of action involves inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. Additionally, its pharmacokinetics may vary, affecting absorption, distribution, metabolism, and excretion. As with many antibiotics, resistance can develop, necessitating careful consideration in therapeutic applications. Overall, this compound represents a significant advancement in antibiotic development, contributing to the ongoing fight against bacterial infections.

Formula: C₃₇H₆₅NO₁₁

Synonyms:

• Erythromycin Impurity 41
• Erythromycin, 8,9-didehydro-9-deoxo-6,12-dideoxy-6,9-epoxy-

Erythromycin Impurity 14

CAS: 33275-72-8

Formula: C₃₇H₆₅NO₁₁

Molecular weight: 699.92

Ref: 4Z-E-2056