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CAS 33279-57-1

:

k-Strophanthoside

Description:
K-Strophanthoside, with the CAS number 33279-57-1, is a cardiac glycoside derived from the seeds of the Strophanthus genus, particularly Strophanthus gratus. It is characterized by its ability to inhibit the Na+/K+ ATPase enzyme, which leads to increased intracellular sodium and calcium concentrations, ultimately enhancing cardiac contractility. This compound exhibits a structure that includes a steroid nucleus with a sugar moiety, contributing to its biological activity. K-Strophanthoside is known for its potential therapeutic applications in treating heart conditions, particularly heart failure and arrhythmias, due to its positive inotropic effects. However, it also has a narrow therapeutic window, necessitating careful monitoring of dosage to avoid toxicity. The substance is typically administered in a controlled medical setting, and its pharmacokinetics can be influenced by various factors, including patient-specific variables and concurrent medications. As with other cardiac glycosides, it is essential to consider potential side effects, such as gastrointestinal disturbances and arrhythmias, when evaluating its use in clinical practice.
Formula:C42H64O19
InChI:InChI=1/C42H64O19/c1-19-36(61-38-35(51)33(49)31(47)27(60-38)17-56-37-34(50)32(48)30(46)26(15-43)59-37)25(54-3)13-29(57-19)58-21-4-9-40(18-44)23-5-8-39(2)22(20-12-28(45)55-16-20)7-11-42(39,53)24(23)6-10-41(40,52)14-21/h12,18-19,21-27,29-38,43,46-53H,4-11,13-17H2,1-3H3/t19-,21+,22?,23+,24-,25+,26-,27-,29+,30-,31-,32+,33+,34-,35-,36-,37-,38+,39-,40+,41+,42+/m1/s1
InChI key:InChIKey=GILGYKHFZXQALF-FBPIOBPTSA-N
SMILES:C(=O)[C@@]12[C@@]3([C@]([C@]4(O)[C@](C)(CC3)[C@H](CC4)C=5COC(=O)C5)(CC[C@]1(O)C[C@@H](O[C@H]6C[C@H](OC)[C@H](O[C@@H]7O[C@H](CO[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](C)O6)CC2)[H])[H]
Synonyms:
  • (3beta,5beta)-3-((O-beta-D-glucopyranosyl-(1.6)-O-beta-D-glucopyranosyl-(1.4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • (3beta,5beta,17xi)-3-{[beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • (3β,5β)-3-[(O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • 3-{[hexopyranosyl-(1->6)hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methylhexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide
  • 5-beta-Card-20(22)-enolide, 3-beta-((O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-
  • Card-20(22)-enolide, 3-((O-beta-D-glucopyranosyl-(1-6)-O-beta-D-glucopyranosyl-(1-4)-2,6-dideoxy-3-O-methyl-beta-D-ribo-hexopyranosyl)oxy)-5,14-dihydroxy-19-oxo-, (3beta,5beta)- (9CI)
  • Card-20(22)-enolide, 3-[(O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→6)-O-β-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-2,6-dideoxy-3-O-methyl-β-<smallcap>D</span>-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-
  • Nsc 7530
  • Strophanthidin + cymarose + beta-glucose + alpha-glucose
  • Strophanthidin + cymarose + beta-glucose + alpha-glucose [German]
  • See more synonyms
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Found 4 products.
  • K-Strophanthoside
    Extrasynthese
    + Info

    K-Strophanthoside

    CAS:
    K-Strophanthoside analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.
    Formula:C42H64O19
    Purity:(HPLC) ≥90%
    Color and Shape:Powder
    Molecular weight:872.96

    Ref: 11-0858

    10mg
    142.00€
  • K-strophanthoside
    Phytolab
    + Info

    K-strophanthoside

    CAS:
    Natural glycoside
    Formula:C42H64O19
    Purity:≥ 90.0 % (HPLC)
    Color and Shape:Powder
    Molecular weight:872.96

    Ref: 5G-82206

    10mg
    301.00€
    50mg
    1,226.00€
    250mg
    5,789.00€
    500mg
    10,897.00€
    1000mg
    20,431.00€
  • K-Strophanthoside
    Biosynth
    + Info

    K-Strophanthoside

    CAS:
    <p>K-Strophanthoside is a cardiac glycoside, which is a bioactive compound derived from the seeds of certain Strophanthus species, a genus of plants native to Africa. This compound exhibits its mode of action by inhibiting the sodium-potassium ATPase enzyme on cell membranes, leading to an increase in intracellular sodium levels. Consequently, the sodium-calcium exchanger is affected, resulting in elevated intracellular calcium concentrations. This cascade enhances cardiac contractility, which can be beneficial in treating certain types of heart failure.</p>
    Formula:C42H64O19
    Purity:Min. 95%
    Molecular weight:872.9 g/mol

    Ref: 3D-IBA27957

    50mg
    763.00€
    100mg
    1,150.00€
  • k-Strophanthoside
    Targetmol
    + Info

    k-Strophanthoside

    CAS:
    k-Strophanthoside is a natural product for research related to life sciences. The catalog number is TN4362 and the CAS number is 33279-57-1.
    Formula:C42H64O19
    Purity:98%
    Color and Shape:Solid
    Molecular weight:872.95

    Ref: TM-TN4362