CAS 33286-22-5: Diltiazem HCl

Description: Diltiazem hydrochloride is a calcium channel blocker primarily used in the treatment of hypertension and angina pectoris. It functions by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to vasodilation and reduced heart rate. This compound is typically presented as a white to off-white crystalline powder, which is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Diltiazem HCl has a molecular formula that reflects its complex structure, which includes a benzothiazepine core. Its pharmacological effects are attributed to its ability to relax vascular smooth muscle and decrease myocardial oxygen demand. The substance is often administered orally or intravenously, depending on the clinical scenario. Side effects may include dizziness, headache, and gastrointestinal disturbances, among others. As with any medication, it is essential to consider contraindications and potential interactions with other drugs. Overall, Diltiazem HCl plays a significant role in cardiovascular therapy, providing relief for patients with specific heart-related conditions.

Formula: C₂₂H₂₇ClN₂O₄S

InChI: InChI=1/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

InChI key: InChIKey=HDRXZJPWHTXQRI-BHDTVMLSSA-N

SMILES: Cl.O=C(OC1C(=O)N(C=2C=CC=CC2SC1C3=CC=C(OC)C=C3)CCN(C)C)C

Synonyms:

• (2S,3S)-(+)-cis-Diltiazem hydrochloride
• (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate
• (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3-yl acetate hydrochloride (1:1)
• (S,S)-Diltiazem hydrochloride
• 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, hydrochloride (1:1), (2S,3S)-
• 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (2S,3S)-
• 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, monohydrochloride, (2S-cis)-
• Adizem
• Altiazem
• Anginyl
• Angipress
• Angizem
• Bi-Teldiem
• Blocalcin 60
• Britiazim
• Bruzem
• Calcicard
• Cardizem
• Cardizem CD
• Cardizem SR
• Citizem
• Cormax
• Crd 401
• Deltazen
• Dicard
• Dilacor
• Dilacor XR
• Diladel
• Dilcardia
• Dilgard
• Dilpral
• Dilrene
• Dilthiazem hydrochloride
• Diltiazem Hydrochloride
• Dilzacard
• Dilzene
• Herbesser
• Kaizem
• Kardil
• Masdil
• Rg 83606
• Tiazac
• Tildiem
• d-cis-3-Acetoxy-2,3-dihydro-5-[2-(dimethylamino)ethyl]-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one hydrochloride
• d-cis-Diltiazem hydrochloride

(+)-cis-Diltiazem Hydrochloride

CAS: 33286-22-542399-41-7

• Formula: C₂₂H₂₆N₂O₄S·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 450.98

(+)-cis-Diltiazem hydrochloride

CAS: 33286-22-5

An L-type calcium channel blocker This Thermo Scientific Chemicals brand product was originally part of …

• Formula: C₂₂H₂₆N₂O₄S•HCl
• Molecular weight: 450.98

Diltiazem impurity standard

CAS: 33286-22-5

• Color and Shape: White

Diltiazem for system suitability CRS

CAS: 33286-22-5

• Formula: C₂₂H₂₇ClN₂O₄S
• Molecular weight: 450.9788

Diltiazem hydrochloride CRS

CAS: 33286-22-5

Diltiazem hydrochloride

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄SHCl
• Purity: 99.7%
• Color and Shape: White
• Molecular weight: 450.13801

Diltiazem Hydrochloride

CAS: 33286-22-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₂₂H₂₆N₂O₄S·HCl
• Color and Shape: White Off-White Powder
• Molecular weight: 414.16133

Dilthiazem hydrochloride

CAS: 33286-22-5

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 450.978g/mol

Diltiazem hydrochloride

CAS: 33286-22-5

Diltiazem hydrochloride (RG 83606 HCl) is a benzothiazepine calcium channel blocking agent with vasodilating action.

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: 98% - 99.65%
• Color and Shape: Odorless White Powder
• Molecular weight: 450.98

Diltiazem Hydrochloride

CAS: 33286-22-5

• Molecular weight: 450.98g/mol

Diltiazem hydrochloride, EP grade

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄S·HCl
• Purity: ≤ 0.1%
• Color and Shape: A white or almost white crystalline powder
• Molecular weight: 450.98

Diltiazem HCl

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄S·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 414.52 36.46

Diltiazem hydrochloride

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄S·HCl
• Purity: 98.0 - 102.0 % (dried basis)
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 450.98

Diltiazem hydrochloride

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄S·ClH
• Color and Shape: Neat
• Molecular weight: 450.98

Diltiazem Hydrochloride

CAS: 33286-22-5

• Formula: C₂₂H₂₆N₂O₄S·ClH
• Color and Shape: Neat
• Molecular weight: 450.98

Diltiazem hydrochloride, 98%

CAS: 33286-22-5

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: 98%
• Color and Shape: Powder, White to off-white
• Molecular weight: 450.98

Diltiazem.HCl

CAS: 33286-22-5

M01693 - Diltiazem.HCl

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: 99.5%
• Color and Shape: Solid
• Molecular weight: 450.9800109863281

Diltiazem Hydrochloride

CAS: 33286-22-5

Applications Diltiazem Hydrochloride is a calcium channel blocker with vasodilating activity. Anti-anginal; anti-hypertensive; anti-arrhythmic (class …

• Formula: C₂₂H₂₆N₂O₄S·ClH
• Color and Shape: White
• Molecular weight: 450.98

Diltiazem hydrochloride

CAS: 33286-22-5

L-type calcium channel blocker

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 450.98 g/mol

Diltiazem

CAS: 33286-22-5

L-type calcium channel blocker

• Formula: C₂₂H₂₇ClN₂O₄S
• Purity: Min. 95%
• Molecular weight: 450.98 g/mol