CAS 333-31-3

Methacholine bromide

Description:

Methacholine bromide is a synthetic quaternary ammonium compound primarily used in medical applications, particularly in the diagnosis of asthma and other respiratory conditions. It acts as a muscarinic agonist, stimulating the parasympathetic nervous system and leading to bronchoconstriction, which helps assess airway hyperreactivity. The substance is characterized by its chemical formula, which includes a bromide ion, contributing to its solubility in water. Methacholine bromide is typically administered via inhalation, allowing for localized effects in the lungs. Its pharmacological properties include a relatively short duration of action, making it suitable for diagnostic purposes. Safety profiles indicate that it may cause side effects such as bronchospasm, cough, or throat irritation, particularly in sensitive individuals. As with any pharmacological agent, it is essential to use methacholine bromide under medical supervision to monitor for adverse reactions and ensure appropriate dosing. Overall, its role in clinical practice underscores its importance in respiratory medicine.

Formula: C₈H₁₈NO₂·Br

InChI: InChI=1S/C8H18NO2.BrH/c1-7(11-8(2)10)6-9(3,4)5;/h7H,6H2,1-5H3;1H/q+1;/p-1

InChI key: InChIKey=MMVPLEUBMWUYIB-UHFFFAOYSA-M

SMILES: C([N+](C)(C)C)C(OC(C)=O)C.[Br-]

Synonyms:

• (2-Hydroxypropyl)trimethylammonium bromide, acetate
• (2R)-2-(acetyloxy)-N,N,N-trimethylpropan-1-aminium
• (2S)-2-(acetyloxy)-N,N,N-trimethylpropan-1-aminium
• 1-Propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, bromide
• 1-propanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, bromide (1:1)
• 2-(acetyloxy)-N,N,N-trimethylpropan-1-aminium bromide
• 2-Acetoxy-N,N,N-trimethylpropan-1-aminium bromide
• 2-Acetyloxypropyl-trimethyl-azaniumbromide
• Acetyl-β-methylcholine bromide
• Ammonium, (2-hydroxypropyl)trimethyl-, bromide, acetate
• Mecholin
• Mecholyl bromide
• Methacholine bromide
• O-Acetyl-β-methylcholine bromide
• Trimethyl-β-acetoxypropylammonium bromide

Methacholine Bromide

CAS: 333-31-3

Formula: C₈H₁₈BrNO₂

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 240.14

Ref: 3B-M0072

Methacholine bromide

CAS: 333-31-3

Muscarinic receptor agonist

Formula: C₈H₁₈NO₂·Br

Color and Shape: White Off-White Powder

Molecular weight: 240.14 g/mol

Ref: 3D-EM70336

Methacholine bromide

CAS: 333-31-3

Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.

Formula: C₈H₁₈BrNO₂

Color and Shape: Solid

Molecular weight: 240.141

Ref: TM-T60332