CAS 333-49-3

2-Thiocytosine

Description:

2-Thiocytosine, with the CAS number 333-49-3, is a sulfur-containing derivative of the nucleobase cytosine. It features a thiol group (-SH) at the 2-position of the pyrimidine ring, which distinguishes it from cytosine. This modification can influence its chemical reactivity and biological properties. 2-Thiocytosine is known for its potential applications in biochemistry and molecular biology, particularly in studies related to nucleic acid interactions and modifications. The presence of the thiol group can enhance its ability to form hydrogen bonds and participate in redox reactions. Additionally, 2-thiocytosine may exhibit altered base-pairing properties compared to its parent compound, which could have implications in nucleic acid stability and function. Its solubility in water and organic solvents can vary, affecting its utility in various experimental conditions. Overall, 2-thiocytosine serves as an important compound for research into nucleobase analogs and their roles in genetic processes.

Formula: C₄H₅N₃S

InChI: InChI=1S/C4H5N3S/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)

InChI key: InChIKey=DCPSTSVLRXOYGS-UHFFFAOYSA-N

SMILES: NC=1NC(=S)N=CC1

Synonyms:

• 2(1H)-Pyrimidinethione, 4-amino-
• 2(1H)-Pyrimidinethione, 6-amino-
• 2(1H)-Pyrimidinone, 4-aminothio-
• 2-Thiocytosine
• 2-mercapto-4-Aminopyrimidine
• 4-Amino-2-mercaptopyrimidine
• 4-Amino-2-pyrimidinethiol
• 6-Amino-2(1H)-pyrimidinethione
• 6-aminopyrimidine-2(1H)-thione
• NSC 211571
• NSC 45755

4-AMINO-2-MERCAPTOPYRIMIDINE

CAS: 333-49-3

Formula: C₄H₅N₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 127.1676

Ref: IN-DA00BY97

6-Aminopyrimidine-2(1H)-thione

CAS: 333-49-3

6-Aminopyrimidine-2(1H)-thione

Purity: 97%

Molecular weight: 127.17g/mol

Ref: 54-OR1005781

4-Amino-2-mercaptopyrimidine

CAS: 333-49-3

4-Amino-2-mercaptopyrimidine is a model system for coordination geometry and the hydroxyl group. It has been shown to have an x-ray crystal structure that can be used to study human serum, activated viruses, and other biological properties. 4-Amino-2-mercaptopyrimidine has been synthesized using a flow system and kinetic energy. The protonation state of 4-amino-2-mercaptopyrimidine is dependent on the pH of the solution and it can exist as two tautomers.

Formula: C₄H₅N₃S

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 127.17 g/mol

Ref: 3D-FA17458

4-amino-1,2-dihydropyrimidine-2-thione

CAS: 333-49-3

Purity: 97%

Molecular weight: 127.1699982

Ref: 10-F615205

4-Amino-2-mercaptopyrimidine

Controlled Product

CAS: 333-49-3

Applications This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells.
References Harbottle, R., et al.: Biochem. J., 217, 485 (1984),

Formula: C₄H₅N₃S

Color and Shape: Neat

Molecular weight: 127.17

Ref: TR-A611930