CAS 33332-28-4

2-Amino-6-Chloropyrazine

Description:

2-Amino-6-chloropyrazine is a heterocyclic organic compound characterized by its pyrazine ring, which contains both an amino group and a chlorine substituent. The presence of the amino group (-NH2) at the 2-position and a chlorine atom at the 6-position contributes to its reactivity and potential applications in various chemical syntheses. This compound is typically a solid at room temperature and is soluble in polar solvents, which is common for many amino-substituted heterocycles. Its molecular structure allows for hydrogen bonding, influencing its physical properties and interactions with other molecules. 2-Amino-6-chloropyrazine is of interest in medicinal chemistry and agrochemicals, as derivatives of pyrazine are often explored for their biological activities. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns. Overall, 2-amino-6-chloropyrazine serves as a valuable building block in organic synthesis and research.

Formula: C₄H₄ClN₃

InChI: InChI=1S/C4H4ClN3/c5-3-1-7-2-4(6)8-3/h1-2H,(H2,6,8)

InChI key: InChIKey=JTPXVCKCLBROOJ-UHFFFAOYSA-N

SMILES: ClC1=NC(N)=CN=C1

Synonyms:

• (6-Chloro-pyrazin-2-yl)-diethyl-amine
• 2-Amino-6-chloro-1,4-pyrazine
• 2-Chloro-6-aminopyrazine
• 2-Pyrazinamine, 6-chloro-
• 6-Amino-2-chloropyrazine
• 6-Chloro-2-aminopyrazine
• 6-Chloro-2-pyrazinamine
• 6-Chloro-2-pyrazinylamine
• 6-Chloro-pyrazin-2-ylamine
• 6-Chloropyrazin-2-amine
• Pyrazinamine, 6-chloro-
• Pyrazine, 2-amino-6-chloro-
• 2-Amino-6-chloropyrazine
• 2-AMINO-6-CHLOROPYRAZINE 98%
• 6-CHLOROPYRAZIN-2-YLAMINE

2-Amino-6-chloropyrazine

CAS: 33332-28-4

Formula: C₄H₄ClN₃

Purity: >98.0%(GC)

Color and Shape: White to Brown powder to crystal

Molecular weight: 129.55

Ref: 3B-A2145

2-Amino-6-chloropyrazine, 95%

CAS: 33332-28-4

2-Amino-6-chloropyrazine is used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy

Formula: C₄H₄ClN₃

Purity: 95%

Molecular weight: 129.55

Ref: 02-H61934

2-Chloro-6-Aminopyrazine

CAS: 33332-28-4

Formula: C₄H₄ClN₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 129.5477

Ref: IN-DA00338O

2-Amino-6-chloropyrazine

CAS: 33332-28-4

Formula: C₄H₄ClN₃

Purity: ≥ 97.0%

Color and Shape: White to yellow or brown crystalline powder

Molecular weight: 129.55

Ref: 7W-GK0932

2-Amino-6-chloropyrazine

CAS: 33332-28-4

2-Amino-6-chloropyrazine

Formula: C₄H₄ClN₃

Purity: 97%

Color and Shape: faint brown to faint red crystalline solid

Molecular weight: 129.55g/mol

Ref: 54-OR11609

2-Amino-6-chloropyrazine

CAS: 33332-28-4

Formula: C₄H₄ClN₃

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 129.55

Ref: 10-F002753

2-Amino-6-chloropyrazine

CAS: 33332-28-4

2-Amino-6-chloropyrazine (2ACP) is an inhibitor that binds to the active site on human protein kinase C (PKC). It has been shown to inhibit PKC by hydrogen bonding with the hydroxide ion, which blocks its catalytic activity. 2ACP has been studied for its potential use in treating cancer and for inhibiting amine oxidases, which are enzymes associated with inflammation and chronic obstructive pulmonary disease. The inhibition of these enzymes may help to reduce stenosis in the lungs or other organs. 2ACP also has been shown to have antimycobacterial activity against Mycobacterium tuberculosis, M. avium complex, and M. leprae by inhibiting DNA synthesis and RNA synthesis. 2ACP inhibits the kinase receptor on the cell membrane that phosphorylates a water molecule into a chlorine atom, which then reacts with hydrogen peroxide to form free radicals that can kill bacteria

Formula: C₄H₄ClN₃

Purity: Min. 95%

Molecular weight: 129.55 g/mol

Ref: 3D-FA15341