CAS 333415-38-6

VU0071063

CAS: 333415-38-6

VU0071063

Purity: ≥98%

Molecular weight: 326.39g/mol

Ref: 54-BUP10552

VU0071063

CAS: 333415-38-6

VU0071063 is a Kir6.2/SUR1 activator.

Formula: C₁₈H₂₂N₄O₂

Purity: 99.33%

Color and Shape: Solid

Molecular weight: 326.39

Ref: TM-T26324

7-(4-(tert-Butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

CAS: 333415-38-6

Purity: 98%

Molecular weight: 326.3999939

Ref: 10-F867478

VU0071063

Controlled Product

CAS: 333415-38-6

VU0071063 is a small molecule that inhibits the mitochondrial membrane potential, which prevents hyperinsulinism. It has been shown to have a pharmacokinetic property that makes it suitable for oral administration. VU0071063 is metabolized in the liver, but penetrates the blood-brain barrier and reaches high concentrations in the pancreas. The compound has a low toxicity profile and shows no appreciable cardiotoxicity. VU0071063 inhibits both subunits of ATP synthase, preventing movement of potassium ions across the mitochondrial membrane and increasing intracellular calcium ion levels. This leads to impaired insulin secretion by pancreatic β-cells, as well as decreased ATP production by other cells.

Formula: C₁₈H₂₂N₄O₂

Purity: Min. 95%

Molecular weight: 326.39 g/mol

Ref: 3D-INA41538