CAS 333419-97-9

N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

Description:

N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide is a chemical compound characterized by its complex structure, which includes a quinoline core, a carboxamide functional group, and a bromophenyl substituent. This compound typically exhibits properties associated with both aromatic and heterocyclic compounds, including potential biological activity due to the presence of the quinoline moiety, which is known for its pharmacological significance. The hydroxyl group contributes to its potential solubility in polar solvents, while the bromine atom may enhance its reactivity and influence its interaction with biological targets. The compound may also exhibit various functional properties such as antimicrobial or anticancer activities, making it of interest in medicinal chemistry. Its molecular structure suggests it could participate in hydrogen bonding and other intermolecular interactions, which are crucial for its biological efficacy. Overall, N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide represents a class of compounds that may have significant applications in drug development and therapeutic research.

Formula: C₁₆H₁₁BrN₂O₃

Synonyms:

• N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide
• 3-Quinolinecarboxamide, N-(3-bromophenyl)-1,2-dihydro-4-hydroxy-2-oxo-
• WAY-339696

N-(3-Bromophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

CAS: 333419-97-9

N-(3-Bromophenyl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

Purity: 98%

Molecular weight: 359.18g/mol

Ref: 54-OR1067260

EGFR T790M/L858R-IN-8

CAS: 333419-97-9

EGFRT790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR, specifically targeting the EGFRT790M/L858R mutations with an IC50 of 56.8 μM. This compound does not show significant antiproliferative effects on cancer cell lines A549, A431, and NHI-H1975.

Formula: C₁₆H₁₁BrN₂O₃

Color and Shape: Solid

Molecular weight: 359.17

Ref: TM-T88087