CAS 333717-40-1
:O-[(Ethoxycarbonyl)Cyanomethylenamino]-N,N,N',N'-Tetramethyluronium Hexafluorophosphate
Description:
O-[(Ethoxycarbonyl)Cyanomethylenamino]-N,N,N',N'-Tetramethyluronium Hexafluorophosphate, with CAS number 333717-40-1, is a chemical compound that serves primarily as a coupling reagent in organic synthesis, particularly in peptide synthesis. It features a tetramethyluronium core, which enhances its reactivity, and is paired with a hexafluorophosphate counterion that contributes to its solubility in polar solvents. The ethoxycarbonyl and cyanomethylene groups provide additional functional versatility, allowing for the formation of various chemical bonds. This compound is typically used in reactions that require the activation of carboxylic acids to facilitate the formation of amide bonds. Its stability under standard laboratory conditions makes it a valuable reagent, although care must be taken due to the potential toxicity of its components. As with many coupling agents, proper handling and disposal protocols should be followed to ensure safety in the laboratory environment.
Formula:C10H17N4O3.PF6
Synonyms:- Hotu
- 6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-aminium hexafluorophosphate
- Hotu O-[(Ethoxycarbonyl)Cyanomethylenamino]-N,N,N',N'-Tetramethyluronium Hexafluorophosphate
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Found 5 products.
O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium Hexafluorophosphate
CAS:Formula:C10H17F6N4O3PPurity:>98.0%(HPLC)(N)Color and Shape:White to Almost white powder to crystalMolecular weight:386.24O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphate
CAS:O-[(Ethoxycarbonyl)cyanomethylenamino]-N,N,N',N'-tetramethyluronium hexafluorophosphatePurity:97%Molecular weight:386.23g/molHOTU
CAS:<p>HOTU is a uronium salt derivative of Oxyma used as a coupling reagent in peptide chemistry. HOTU is highly reactive, generates water-soluble by-products, therefore the purification is easily achieved. HOTU forms an acyl oxime upon activation of the carboxylic acid and this reacts with the amine generating the final product.</p>Formula:C10H17F6N4O3PPurity:Min. 95%Color and Shape:PowderMolecular weight:386.23 g/mol




