CAS 33375-06-3

R-(+)-α-methylbenzyl isocyanate

Description:

R-(+)-α-methylbenzyl isocyanate is an organic compound characterized by its isocyanate functional group, which is known for its reactivity, particularly in forming ureas and other derivatives. This compound features a chiral center, contributing to its enantiomeric form, which can exhibit different biological activities compared to its counterpart. It is typically a colorless to pale yellow liquid with a distinctive odor. The presence of the isocyanate group makes it a valuable intermediate in organic synthesis, particularly in the production of pharmaceuticals, agrochemicals, and polymers. Additionally, R-(+)-α-methylbenzyl isocyanate is sensitive to moisture and can react with water to form corresponding amines and carbon dioxide. Safety precautions are essential when handling this compound, as isocyanates can be irritants and pose health risks upon exposure. Overall, its unique structural features and reactivity make it a significant compound in various chemical applications.

Formula: C₉H₉NO

InChI: InChI=1/C9H9NO/c1-8(10-7-11)9-5-3-2-4-6-9/h2-6,8H,1H3/t8-/m1/s1

InChI key: InChIKey=JJSCUXAFAJEQGB-MRVPVSSYSA-N

SMILES: [C@@H](N=C=O)(C)C1=CC=CC=C1

Synonyms:

• (+)-(R)-α-Phenethyl isocyanate
• (+)-1-Phenylethyl isocyanate
• (+)-α-Methylbenzyl isocyanate
• (+)-α-Phenylethyl isocyanate
• (R)-(+)-1-Phenethyl isocyanate
• (R)-(+)-1-Phenylethyl Isocyanate
• (R)-(+)-Alpha-methylbenzyl isocyanate
• (R)-(1-Isocyanatoethyl)benzene
• (R)-α-Phenylethyl isocyanate
• Benzene, (1-isocyanatoethyl)-, (R)-
• Benzene, [(1R)-1-isocyanatoethyl]-
• [(1R)-1-Isocyanatoethyl]benzene
• ISOCYANIC ACID (R)-(+)-1-PHENYLETHYL ESTER
• (R) METHYL BENZYLISOCYANATE
• (R)-(+)-A-METHYLBENZYL ISOCYANATE
• ISOCYANIC ACID (R)-(+)-ALPHA-METHYLBENZYL ESTER
• zR{-(+)-1-Phenylethyl isocyanate
• IsocyanicAcid(R)-(+)-α-MethylbenzylEster
• (R)(+)-ALPHA-PHENETHYL ISOCYANATE
• R-(+)-alfa-Methylbenzyl Isocyanate
• (r)-(+)-à-methylbenzyl isocyanate
• (R)-1-PHENYLETHYLISOCYANATE
• R-(+)-Phenethyl Isocyanate
• R-(+)-1-PHENYLETHYL ISOCYANATE STAB
• (R)-(+)-ALPHA-METHYLBENZYL ISOCYANATE, 9 9%
• IsocyanicAcid-(R)-(+)-á-MethylbenzylEster

(R)-(+)-α-Methylbenzyl Isocyanate

CAS: 33375-06-3

Formula: C₉H₉NO

Purity: >98.0%(GC)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 147.18

Ref: 3B-I0334

(R)-(+)-1-Phenylethyl isocyanate, 99%

CAS: 33375-06-3

(R)-1-phenylethyl isocyanate is used in the derivatisation of alcohols, thiocarbamates and hydroxy fatty acids. (R)-1-phenylethyl isocyanate moderately inhibited both BP-DNA adducts. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documen

Formula: C₉H₉NO

Purity: 99%

Color and Shape: Clear to slightly hazy, colorless, Liquid

Molecular weight: 147.18

Ref: 02-L10305

(R)-(+)-α-Methylbenzyl isocyanate

CAS: 33375-06-3

Formula: C₉H₉NO

Purity: 95%

Color and Shape: Liquid

Molecular weight: 147.1739

Ref: IN-DA00327G

(R)-(+)-α-Methylbenzyl isocyanate

CAS: 33375-06-3

(R)-(+)-α-Methylbenzyl isocyanate

Purity: 95%

Molecular weight: 147.17g/mol

Ref: 54-OR1008411

(+)-α-Methylbenzyl isocyanate, 99%

CAS: 33375-06-3

Formula: C₉H₉NO

Purity: ≥ 99.0%

Color and Shape: Clear to faintly turbid, colourless to faint yellow liquid

Molecular weight: 147.18

Ref: 7W-GK2212

R-(+)-a-Methylbenzyl isocyanate

CAS: 33375-06-3

Formula: C₉H₉NO

Purity: 98.0%

Color and Shape: Liquid, Clear colourless - Very pale yellow liquid

Molecular weight: 147.177

Ref: 10-F013633

(R)-(+)-1-Phenylethyl Isocyanate

CAS: 33375-06-3

Formula: C₉H₉NO

Molecular weight: 147.18

Ref: 4Z-I-131009

(R)-(+)-α-Methylbenzyl isocyanate

Controlled Product

CAS: 33375-06-3

Stability Very Moisture sensitive
Applications (R)-(+)-α-Methylbenzyl isocyanate is used in the synthesis of non-steroidal mineralocorticoid receptor antagonists. Also used in the synthesis of antiviral and anti-HIV agents such as DPC 961.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yang, C. et al.: ACS Med. Chem. Lett., 6, 461 (2015); Andrushko, V. (2013). Stereoselective Synthesis of Drugs and Natural Products. Hoboken, NJ: John WIley & Sons.

Formula: C₉H₉NO

Color and Shape: Neat

Molecular weight: 147.17

Ref: TR-M291410