CAS 333753-67-6

Linezolid impurity B

Description:

Linezolid impurity B, with the CAS number 333753-67-6, is a chemical compound associated with the antibiotic linezolid, which is used primarily to treat infections caused by Gram-positive bacteria. This impurity is a byproduct that may arise during the synthesis or degradation of linezolid. While specific characteristics such as molecular weight, structure, and solubility may vary, impurities like this are typically characterized by their potential impact on the efficacy and safety of the primary drug. Linezolid impurity B may exhibit different pharmacological properties compared to the parent compound, and its presence in pharmaceutical formulations is closely monitored to ensure compliance with regulatory standards. Analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry are commonly employed to identify and quantify such impurities in drug formulations. Understanding the characteristics of impurities is crucial for maintaining the quality and integrity of pharmaceutical products.

Linezolid Impurity 80

CAS: 333753-67-6

Formula: C₁₅H₂₂FN₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 311.36

Ref: 4Z-L-079

N-[(2R)-3-(3-Fluoro-4-morpholinoanilino)-2-hydroxypropyl]acetamide

CAS: 333753-67-6

Color and Shape: Neat

Ref: 86-MM3300.16

N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]acetamide

Controlled Product

CAS: 333753-67-6

Applications N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]acetamide is an impurity of Linezolid (L466500).
References Gregory, W., et al.: J. Med. Chem., 32, 1673 (1989), Shinabarger, D., et al.: J. Antimicrob. Agents Chemother., 41, 2132 (1997),

Formula: C₁₅H₂₂FN₃O₃

Color and Shape: White To Off-White

Molecular weight: 311.35

Ref: TR-F594950

N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide

CAS: 333753-67-6

N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide is an impurity in a high purity analytical reference standard of 3-fluoro-4-(4-morpholinyl)aniline. It is also a metabolite that may be present in drug products containing 3-fluoro-4-(4-morpholinyl)aniline as the active ingredient, such as fluoroquinolones. N-[(2R)-3-{[3-Fluoro-4-(4-morpholinyl)phenyl]amino}-2-hydroxypropyl]acetamide has been shown to inhibit DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhib

Formula: C₁₅H₂₂FN₃O₃

Purity: Min. 95%

Molecular weight: 311.35 g/mol

Ref: 3D-IF58040

Linezolid Descarbonyl (R)-Isomer

CAS: 333753-67-6

Formula: C₁₅H₂₂FN₃O₃

Molecular weight: 311.36

Ref: ST-EA-CP-L40017