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CAS 3338-32-7

:

Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester

Description:
Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester, with the CAS number 3338-32-7, is a chemical compound that serves as a derivative of aspartic acid, an amino acid important in biochemistry. This compound features a Z-protecting group, which enhances its stability and solubility, making it suitable for various synthetic applications, particularly in peptide synthesis. The presence of the succinimidyl ester moiety indicates that it can be used for coupling reactions, facilitating the formation of amide bonds with nucleophiles, such as amines. The tert-butyl group contributes to the steric hindrance, which can influence the reactivity and selectivity of the compound in chemical reactions. Z-L-aspartic acid 4-tert-butyl-1-(N-succinimidyl) ester is often utilized in the development of pharmaceuticals and bioconjugates, owing to its ability to selectively modify biomolecules. Its stability under physiological conditions and compatibility with various functional groups make it a valuable tool in organic synthesis and medicinal chemistry.
Formula:C20H24N2O8
InChI:InChI=1/C20H24N2O8/c1-20(2,3)29-17(25)11-14(18(26)30-22-15(23)9-10-16(22)24)21-19(27)28-12-13-7-5-4-6-8-13/h4-8,14H,9-12H2,1-3H3,(H,21,27)
InChI key:InChIKey=JUMSBOKRGDETHL-AWEZNQCLSA-N
SMILES:O(C([C@@H](NC(OCC1=CC=CC=C1)=O)CC(OC(C)(C)C)=O)=O)N2C(=O)CCC2=O
Synonyms:
  • <span class="text-smallcaps">L</span>-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
  • Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., <span class="text-smallcaps">L</span>-
  • Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (3S)-
  • Butanoic acid, 4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxo-3-[[(phenylmethoxy)carbonyl]amino]-, 1,1-dimethylethyl ester, (S)-
  • N-Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-aspartic acid 5-tert-butyl-1-hydroxysuccinimide diester
  • Succinimide, N-[(N-carboxy-<span class="text-smallcaps">L</span>-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
  • Z-Asp(Otbu)-Osu
  • Succinimide, N-[(N-carboxy-L-α-aspartyl)oxy]-, N-benzyl tert-butyl ester
  • Aspartic acid, N-carboxy-, N-benzyl 4-tert-butyl ester, succinimido deriv., L-
  • L-Aspartic acid, N-[(phenylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) 1-(2,5-dioxo-1-pyrrolidinyl) ester
  • See more synonyms
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