CAS 33417-27-5

2-Amino-9H-fluoren-9-ol

Description:

2-Amino-9H-fluoren-9-ol, with the CAS number 33417-27-5, is an organic compound characterized by its structure, which features a fluorenyl group substituted with an amino group and a hydroxyl group. This compound typically appears as a solid and is known for its potential applications in organic synthesis and as a building block in the development of pharmaceuticals and dyes. It exhibits properties such as solubility in polar solvents, which is influenced by the presence of the hydroxyl group, allowing for hydrogen bonding. The amino group contributes to its basicity and reactivity, making it a versatile intermediate in various chemical reactions, including nucleophilic substitutions and coupling reactions. Additionally, 2-Amino-9H-fluoren-9-ol can participate in various biological activities, which may be of interest in medicinal chemistry. Safety data should be consulted for handling, as with any chemical substance, to ensure proper precautions are taken during its use in laboratory or industrial settings.

Formula: C₁₃H₁₁NO

InChI: InChI=1/C13H11NO/c14-8-5-6-10-9-3-1-2-4-11(9)13(15)12(10)7-8/h1-7,13,15H,14H2

InChI key: InChIKey=TWLNNLHYUBGLHG-UHFFFAOYSA-N

SMILES: OC1C=2C(C=3C1=CC=CC3)=CC=C(N)C2

Synonyms:

• 2-Amino-9-Fluorenone
• 2-amino-9H-fluoren-9-ol
• 9H-Fluoren-9-ol, 2-amino-
• Fluoren-9-ol, 2-amino-
• NSC 12389
• (±)-2-Amino-9-hydroxyfluorene
• 2-Amino-9-hydroxyfluorene
• 2-AMINO-9-FLUORENOL
• 2-amino-fluoren-9-o
• 2-AMINO-9-FLUOROENONE

2-Amino-9-fluorenol

CAS: 33417-27-5

2-Amino-9-fluorenol is a hydrophobic compound that binds to RNA. 2-Amino-9-fluorenol has been shown to have a binding constant of 1.2 x 10, which is much higher than the binding constant for curculigoside (5.2 x 10). This substance has shown to be an effective inhibitor of RNA synthesis in HL60 cells and various bacterial strains by binding to the ribose moiety of RNA and preventing transcription. The metabolic pathway for 2-amino-9-fluorenol consists of two steps: one involving a reactive intermediate, potassium ion, and another with methylamine as the reactant. These reactions are catalyzed by enzymes such as acetaldehyde dehydrogenase and amino transferases, respectively.

Formula: C₁₃H₁₁NO

Purity: Min. 95%

Color and Shape: Yellow solid.

Molecular weight: 197.23 g/mol

Ref: 3D-FA66891