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CAS 3343-28-0

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N-Phthaloyl-DL-glutamic anhydride

Description:
N-Phthaloyl-DL-glutamic anhydride, with the CAS number 3343-28-0, is a chemical compound derived from glutamic acid, characterized by the presence of a phthaloyl group. This substance typically appears as a white to off-white solid and is known for its role as a reagent in organic synthesis, particularly in the formation of peptide bonds and the protection of amino acids. It is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane, but generally insoluble in water. The compound exhibits reactivity due to the anhydride functional group, which can undergo hydrolysis or react with nucleophiles, making it useful in various chemical transformations. Additionally, N-Phthaloyl-DL-glutamic anhydride is utilized in the pharmaceutical industry for the synthesis of bioactive compounds and in the development of drug delivery systems. Safety precautions should be observed when handling this compound, as it may cause irritation to the skin and eyes.
Formula:C13H9NO5
InChI:InChI=1S/C13H9NO5/c15-10-6-5-9(13(18)19-10)14-11(16)7-3-1-2-4-8(7)12(14)17/h1-4,9H,5-6H2
InChI key:InChIKey=ICDLEMPZXFCQEB-UHFFFAOYSA-N
SMILES:O=C1N(C(=O)C=2C1=CC=CC2)C3C(=O)OC(=O)CC3
Synonyms:
  • 1H-Isoindole-1,3(2H)-dione, 2-(tetrahydro-2,6-dioxo-2H-pyran-3-yl)-
  • 2-(2,6-Dioxo-tetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione
  • 2-(2,6-Dioxo-tetrahydro-pyran-3-yl)-isoindole-1,3-dione
  • 2-(2,6-Dioxooxan-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
  • 2-(2,6-Dioxooxan-3-yl)isoindole-1,3-dione
  • 2-(2,6-Dioxotetrahydropyran-3-Yl)Isoindoline-1,3-Dione
  • 2-(2,6-Dioxotetrahydropyran-3-yl)isoindol-1,3-dione
  • 2-(Tetrahydro-2,6-dioxo-2H-pyran-3-yl)-1H-isoindole-1,3(2H)-dione
  • 2-Phthalimidoglutaric acid anhydride
  • 2-Phthalimidoglutaric anhydride
  • See more synonyms
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