CAS 33430-62-5

Disodium 5′-dTMP

Description:

Disodium 5′-dTMP, also known as disodium 5'-deoxythymidine monophosphate, is a nucleotide derivative that plays a crucial role in various biochemical processes, particularly in DNA synthesis and metabolism. It is characterized by its structure, which includes a deoxyribose sugar, a phosphate group, and a thymine base. The presence of two sodium ions in its disodium form enhances its solubility in aqueous solutions, making it suitable for various laboratory applications, including molecular biology and biochemistry. This compound is often utilized in studies related to nucleic acid synthesis, enzymatic reactions, and as a substrate in phosphorylation reactions. Its stability and reactivity are influenced by the pH of the solution, and it is generally stored under controlled conditions to prevent degradation. As a nucleotide, it is integral to the formation of DNA, and its derivatives are essential in the development of pharmaceuticals and biotechnological applications.

Formula: C₁₀H₁₅N₂O₈P·2Na

InChI: InChI=1S/C10H15N2O8P.2Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(20-8)4-19-21(16,17)18;;/h3,6-8,13H,2,4H2,1H3,(H,11,14,15)(H2,16,17,18);;/t6-,7+,8+;;/m0../s1

InChI key: InChIKey=QCGVBSTURNXKRH-ZJWYQBPBSA-N

SMILES: O=C1N([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)C2)C=C(C)C(=O)N1.[Na]

Synonyms:

• 2'-Deoxythymidine-5'-monophosphate,disodium salt
• 5-Thymidylic acid disodium salt
• 5′-Thymidylic acid, sodium salt (1:2)
• Disodium 5′-dTMP
• Disodium TMP
• TTP-Na2
• Thymidine-5'-Monophosphate Disodium
• Thymidine-5'-Monophosphate Disodium Salt
• Thymidine-5-triphosphoric acid disodium salt
• dTMP.Na2
• disodium 5'-O-phosphonatothymidine

Thymidine 5'-Monophosphate Disodium Salt

CAS: 33430-62-5

Formula: C₁₀H₁₃N₂Na₂O₈P

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 366.17

Ref: 3B-T0845

Thymidine-5'-monophosphate disodium salt

CAS: 33430-62-5

Thymidine-5'-monophosphate disodium salt is a nucleoside monophosphate used to prepare thymidine diphosphate by thymidylate kinase (TMPK) which is a nucleoside monophosphate kinase. In addition to this, it serves as a constituent of deoxyribonucleic acid. This Thermo Scientific Chemicals brand produ

Formula: C₁₀H₁₃N₂Na₂O₈P

Color and Shape: Powder, White

Molecular weight: 366.17

Ref: 02-J60747

5'-Thymidylic acid, disodium salt

CAS: 33430-62-5

Formula: C₁₀H₁₃N₂Na₂O₈P

Purity: 98%

Color and Shape: Solid

Molecular weight: 366.1721

Ref: IN-DA00I6KX

Sodium ((2R,3S,5R)-3-Hydroxy-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Tetrahydrofuran-2-Yl)Methyl Phosphate

CAS: 33430-62-5

Sodium ((2R,3S,5R)-3-Hydroxy-5-(5-Methyl-2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)Tetrahydrofuran-2-Yl)Methyl Phosphate

Purity: 97%

Molecular weight: 366.17g/mol

Ref: 54-OR1014926

Thymidine-5'-monophosphate disodium salt

CAS: 33430-62-5

Thymidine-5'-monophosphate disodium salt

Purity: ≥98%

Molecular weight: 384.19g/mol

Ref: 54-BUP17126

Thymidine 5''-monophosphate disodium salt hydrate

CAS: 33430-62-5

Formula: C₁₀H₁₃N₂Na₂O₈P·xH₂O

Purity: ≥ 99.0% (anhydrous basis)

Color and Shape: White or almost white powder

Molecular weight: 366.18 (anhydrous)

Ref: 7W-GE0125

Thymidine-5'-monophosphate disodium salt

CAS: 33430-62-5

TMP disodium salt, found in DNA, induces chromosomal damage in mammals when thymidine is lacking.

Formula: C₁₀H₁₅N₂Na₂O₉P

Purity: 99.32% - >99.99%

Color and Shape: Solid

Molecular weight: 384.19

Ref: TM-T4730

Thymidine 5'-Monophosphate Disodium Salt Hydrate

Controlled Product

CAS: 33430-62-5

Stability Hygrosopic
Applications A nucleoside monophosphate derived from phosphorylation of Thymidine (T412000). It is converted to Thymidine diphosphate by Thymidylate kinase (TMPK), a nucleoside monophosphate kinase. A constituent of Deoxyribonucleic Acid.
References Van de Vorst, A. et al.: Biochim. Biophys. Acta Nucleic Acids Protein Synth., 238, 417 (1971);

Formula: C₁₀H₁₃N₂Na₂O₈P•xH₂O

Color and Shape: Neat

Molecular weight: 366.17

Ref: TR-T412015

Thymidine-5'-monophosphate disodium salt

CAS: 33430-62-5

Thymidine-5'-monophosphate disodium salt is a nucleoside that is synthesized by reductive phosphorylation of thymidine. It is a substrate for nucleotide synthesis and can be used as a reagent in the synthesis of oligonucleotides. Thymidine-5'-monophosphate disodium salt can be reduced to form thymidine, which can then be converted to 5-thio-2'-deoxyuridylate or 5-thio-2'-deoxycytidylate. This conversion takes place through the cleavage reaction of the thymidine residue from the disodium salt.

Formula: C₁₀H₁₃N₂Na₂O₈P

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 366.17 g/mol

Ref: 3D-NT02975

2′-Deoxythymidine-5′-monophosphate disodium salt

CAS: 33430-62-5

Formula: C₁₀H₁₃N₂Na₂O₈P

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 366.173

Ref: 10-F334251

Thymidine-5-Monophosphate Disodium Salt (TMP-Na2) extrapure, 98%

CAS: 33430-62-5

Formula: C₁₀H₁₃N₂O₈PNa₂

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 366.17

Ref: SR-45764