CAS 33468-35-8

6-Chloro-L-tryptophan

Description:

6-Chloro-L-tryptophan is an amino acid derivative that is a halogenated form of L-tryptophan, an essential amino acid important for protein synthesis and a precursor to neurotransmitters such as serotonin. This compound features a chlorine atom substituted at the sixth position of the indole ring, which can influence its biochemical properties and interactions. It is typically characterized by its white to off-white crystalline appearance and is soluble in water and organic solvents, depending on the pH. The presence of the chlorine atom can enhance its reactivity and alter its biological activity compared to its non-chlorinated counterpart. 6-Chloro-L-tryptophan is often used in biochemical research, particularly in studies related to protein structure and function, as well as in the synthesis of various pharmaceuticals. Its unique properties make it a valuable tool in the exploration of metabolic pathways and the development of therapeutic agents. As with many chemical substances, safety precautions should be observed when handling it, given its potential biological effects.

Formula: C₁₁H₁₁ClN₂O₂

InChI: InChI=1S/C11H11ClN2O2/c12-7-1-2-8-6(3-9(13)11(15)16)5-14-10(8)4-7/h1-2,4-5,9,14H,3,13H2,(H,15,16)/t9-/m0/s1

InChI key: InChIKey=FICLVQOYKYBXFN-VIFPVBQESA-N

SMILES: C([C@@H](C(O)=O)N)C=1C=2C(NC1)=CC(Cl)=CC2

Synonyms:

• (2S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid
• (S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid
• 6-Chloro-<span class="text-smallcaps">L</span>-tryptophan
• 6-Chloro-L-tryptophan
• 6-Chloro-L-tryptophane
• 6-Chlorotryptophan
• <span class="text-smallcaps">L</span>-6-Chlorotryptophan
• <span class="text-smallcaps">L</span>-Tryptophan, 6-chloro-
• H-6-Cl-Trp-OH
• L-6-Chlorotryptophan
• Tryptophan, 6-chloro-, <span class="text-smallcaps">L</span>-
• Tryptophan,6-chloro-, L-
• L-Tryptophan, 6-chloro-
• -2-Amino-3-(6-chloro-1H-indol-3-yl)

6-Chloro-L-tryptophan

CAS: 33468-35-8

Formula: C₁₁H₁₁ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.6702

Ref: IN-DA00BZK2

6-Chloro L-Tryptophan

CAS: 33468-35-8

Molecular weight: 238.67

Ref: 7W-GM2763

6-Chloro-L-tryptophan

CAS: 33468-35-8

6-Chloro-L-tryptophan

Purity: 97%

Molecular weight: 238.67g/mol

Ref: 54-OR964662

6-Chloro L-Tryptophan

Controlled Product

CAS: 33468-35-8

Formula: C₁₁H₁₁ClN₂O₂

Color and Shape: Neat

Molecular weight: 238.67

Ref: TR-C423210

6-Chloro L-tryptophan

CAS: 33468-35-8

6-Chloro L-tryptophan is an aminotransferase inhibitor that is activated by the enzyme, aminotransferase. 6-Chloro L-tryptophan has been shown to inhibit the growth of tumour cells, which may be due to its ability to induce apoptosis and inhibit the production of tumour necrosis factor alpha (TNFα). This drug has also been shown to exhibit antiinflammatory effects and can inhibit the activation of microglia in human brain cells. 6-Chloro L-tryptophan is activated by liver cells and human macrophages, leading to the inhibition of 3-hydroxyanthranilic acid synthesis and the neutralization of acidic conditions. It also inhibits uptake in thp-1 cells, a type of white blood cell that lines blood vessels in lymph nodes. In addition, 6-chloro L-tryptophan has been shown to have antiviral effects

Formula: C₁₁H₁₁ClN₂O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 238.67 g/mol

Ref: 3D-FC19949

6-Chloro-L-tryptophan

CAS: 33468-35-8

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Formula: C₁₁H₁₁ClN₂O₂

Purity: Min. 97 Area-%

Molecular weight: 238.67 g/mol

Ref: 3D-W-204220

(S)-2-Amino-3-(6-chloro-1H-indol-3-yl)propanoic acid

CAS: 33468-35-8

Formula: C₁₁H₁₁ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 238.67

Ref: 10-F329498