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CAS 334758-19-9

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4’-Raloxifene-β-D-glucopyranoside

Description:
4’-Raloxifene-β-D-glucopyranoside, identified by its CAS number 334758-19-9, is a glycosylated derivative of raloxifene, a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of osteoporosis in postmenopausal women. This compound features a β-D-glucopyranoside moiety, which enhances its solubility and bioavailability compared to its parent compound. The structural modification allows for improved pharmacokinetic properties, potentially leading to more effective therapeutic outcomes. As a SERM, 4’-Raloxifene-β-D-glucopyranoside exhibits tissue-selective estrogenic activity, which means it can mimic or block estrogen's effects in different tissues, making it useful in managing conditions influenced by estrogen levels. Its safety profile and efficacy are subjects of ongoing research, particularly in relation to its potential benefits in cardiovascular health and cancer prevention. Overall, this compound represents an important area of study in medicinal chemistry, particularly in the development of targeted therapies for hormone-related conditions.
Formula:C34H37NO9S
Synonyms:
  • 4'-Raloxifene-β-D-glucopyranoside
  • 4’-Raloxifene-β-D-glucopyranoside
  • Methanone, [2-[4-(β-D-glucopyranosyloxy)phenyl]-6-hydroxybenzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-
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