CAS 334826-98-1

Gisadenafil

Description:

Gisadenafil, identified by its CAS number 334826-98-1, is a chemical compound that belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. It is primarily researched for its potential use in treating erectile dysfunction and pulmonary arterial hypertension. The compound works by enhancing the effects of nitric oxide, leading to increased blood flow to specific areas of the body. Gisadenafil exhibits a relatively high selectivity for PDE5 over other phosphodiesterases, which contributes to its therapeutic efficacy and reduced side effects. Its chemical structure includes a heterocyclic ring system, which is common among PDE5 inhibitors, and it is typically administered in oral form. The pharmacokinetics of Gisadenafil involve absorption, distribution, metabolism, and excretion processes that are crucial for its effectiveness and safety profile. As with other medications in its class, potential side effects may include headaches, flushing, and gastrointestinal disturbances. Ongoing research continues to explore its full therapeutic potential and safety in various populations.

Formula: C₂₃H₃₃N₇O₅S

InChI: InChI=1S/C23H33N7O5S/c1-5-18-19-20(27-30(18)12-13-34-4)22(31)26-21(25-19)17-14-16(15-24-23(17)35-7-3)36(32,33)29-10-8-28(6-2)9-11-29/h14-15H,5-13H2,1-4H3,(H,25,26,31)

InChI key: InChIKey=YPFZMBHKIVDSNR-UHFFFAOYSA-N

SMILES: C(C)C1=C2C(=NN1CCOC)C(=O)N=C(N2)C3=C(OCC)N=CC(S(=O)(=O)N4CCN(CC)CC4)=C3

Synonyms:

• 2-(Methoxyethyl)-5-[2-ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)pyridin-3-yl]-3-ethyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 5-[2-Ethoxy-5-(4-ethylpiperazin-1-ylsulfonyl)pyridin-3-yl]-3-ethyl-2-(2-methoxyethyl)-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one
• 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-
• Piperazine, 1-[[6-ethoxy-5-[3-ethyl-4,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridinyl]sulfonyl]-4-ethyl-
• Uk 369003

Gisadenafil

CAS: 334826-98-1

Gisadenafil

Purity: ≥98%

Molecular weight: 519.62g/mol

Ref: 54-BUP04353

Gisadenafil

CAS: 334826-98-1

Formula: C₂₃H₃₃N₇O₅S

Molecular weight: 519.62

Ref: 4Z-G-181001

Gisadenafil-d5

CAS: 334826-98-1

Formula: C₂₃H₂₈D₅N₇O₅

Molecular weight: 524.65

Ref: 4Z-G-181003

Gisadenafil

CAS: 334826-98-1

Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.

Formula: C₂₃H₃₃N₇O₅S

Purity: 98.82% - 99.50%

Color and Shape: Solid

Molecular weight: 519.62

Ref: TM-T15381