CAS 334951-90-5

1H-Indole-6-carboxamide,N-ethyl-2,3-dihydro-N-methyl-2-oxo-3-[phenyl[[4-(1-piperidinylmethyl)phenyl]amino]methylene]-, (3Z)-

CAS: 334951-90-5

Formula: C₃₁H₃₄N₄O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 494.6273

Ref: IN-DA01FS4L

BIBF0775

CAS: 334951-90-5

BIBF0775

Purity: ≥98%

Molecular weight: 494.63g/mol

Ref: 54-BUP12517

BIBF0775

CAS: 334951-90-5

BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).

Formula: C₃₁H₃₄N₄O₂

Purity: 99.45% - 99.79%

Color and Shape: Solid

Molecular weight: 494.63

Ref: TM-T5197

BIBF0775

CAS: 334951-90-5

BIBF0775

Purity: 97%

Molecular weight: 494.63g/mol

Ref: 54-BISN0074

BIBF0775

CAS: 334951-90-5

BIBF0775 is a small-molecule inhibitor of the platelet-derived growth factor receptor (PDGFR) that was developed for the treatment of cancer. It binds to the kinase domain of PDGFR and inhibits the activity of this protein. BIBF0775 is active against a number of cancers, including glioma, lung cancer, pancreatic cancer, and prostate cancer. The effective dose has been shown to be 0.1 μM in cells grown in vitro and 10 mg/kg in mice bearing xenograft tumors.

Formula: C₃₁H₃₄N₄O₂

Purity: Min. 95%

Molecular weight: 494.63 g/mol

Ref: 3D-JNA95190