CAS 334998-36-6

N-[(3S,5S)-1-(3H-1,2-benzodioxol-6-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-butanamide

Description:

The chemical substance N-[(3S,5S)-1-(3H-1,2-benzodioxol-6-ylmethyl)-5-(piperazine-1-carbonyl)pyrrolidin-3-yl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethyl-butanamide, with CAS number 334998-36-6, is a complex organic compound characterized by its multi-functional structure. It features a pyrrolidine ring, which is a five-membered nitrogen-containing heterocycle, and incorporates both piperazine and benzodioxole moieties, contributing to its potential biological activity. The presence of methoxy and carbonyl groups enhances its chemical reactivity and solubility properties. This compound is likely to exhibit significant pharmacological properties, making it of interest in medicinal chemistry, particularly in the development of therapeutic agents. Its stereochemistry, indicated by the (3S,5S) configuration, suggests specific spatial arrangements that may influence its interaction with biological targets. Overall, this compound's intricate structure and functional groups suggest potential applications in drug discovery and development, although specific biological activities would require further investigation through experimental studies.

Formula: C₃₁H₄₂N₄O₅

InChI: InChI=1/C31H42N4O5/c1-31(2,3)17-29(36)35(19-22-6-5-7-26(14-22)38-4)25-16-27(30(37)33-12-10-32-11-13-33)34(20-25)18-23-8-9-24-21-39-40-28(24)15-23/h5-9,14-15,25,27,32H,10-13,16-21H2,1-4H3/t25-,27-/m0/s1

SMILES: CC(C)(C)CC(=O)N(Cc1cccc(c1)OC)[C@H]1C[C@@H](C(=O)N2CCNCC2)N(Cc2ccc3COOc3c2)C1

CUR 61414

CAS: 334998-36-6

Formula: C₃₁H₄₂N₄O₅

Molecular weight: 550.70

Ref: 4Z-U-106001

CUR61414

CAS: 334998-36-6

CUR61414

Purity: ≥95%

Molecular weight: 550.69g/mol

Ref: 54-BUP08456

CUR 61414-d8

CAS: 334998-36-6

Formula: C₃₁H₃₄D₈N₄O₅

Molecular weight: 558.75

Ref: 4Z-U-106002

CUR 61414

Controlled Product

CAS: 334998-36-6

Applications CUR 61414 is a proline derivative as mediator of hedgehog signaling pathways for pharmaceutical and cosmetic uses. CUR 61414 is a Nucleoside analog. CUR 61414 is an antimetabolite antitumor combination Gemcitabine cancer treatment.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Van der Riet, P., et al.: Cancer Res., 54, 25 (1994), Hahn, H., et al.: Cell, 85, 841 (1996), Johnson, R., et al.: Science, 272, 1668 (1996), Ingham, P., et al.: Genes Dev., 15, 3059 (2001),

Formula: C₃₁H₄₂N₄O₅

Color and Shape: Neat

Molecular weight: 550.69

Ref: TR-C835000

CUR 61414

CAS: 334998-36-6

Antagonist of hedgehog signaling pathway activator Smoothened; antineoplastic

Formula: C₃₁H₄₂N₄O₅

Purity: Min. 95%

Molecular weight: 550.69 g/mol

Ref: 3D-FB20593

CUR61414

CAS: 334998-36-6

CUR61414 is a cell-permeable inhibitor of Hedgehog signaling pathway (IC50 =100-200 nM) and selectively binds to smoothened (Ki = 44 nM).

Formula: C₃₁H₄₂N₄O₅

Purity: 97.34% - 98%

Color and Shape: Solid

Molecular weight: 550.69

Ref: TM-T15019