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CAS 33507-63-0

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Substance P

Description:
Substance P is a neuropeptide that functions primarily as a neurotransmitter and neuromodulator in the central and peripheral nervous systems. It is composed of eleven amino acids and is part of the tachykinin family of peptides. Characteristically, Substance P is involved in the transmission of pain signals and plays a significant role in inflammatory responses, stress, and anxiety. It binds to the neurokinin-1 (NK1) receptor, which is widely distributed in the brain and other tissues, influencing various physiological processes. In addition to its role in pain perception, Substance P is implicated in the regulation of mood, anxiety, and the immune response. The peptide is typically found in high concentrations in areas of the brain associated with pain and emotional regulation. Due to its involvement in various pathophysiological conditions, Substance P has been a target for therapeutic interventions in pain management and psychiatric disorders. Its CAS number, 33507-63-0, is used for identification in chemical databases and regulatory contexts.
Synonyms:
  • 2: PN: JP2005049164 SEQID: 2 claimed protein
  • 21: PN: WO0181408 SEQID: 44 claimed protein
  • 36: PN: WO2007058336 SEQID: 36 claimed protein
  • 44: PN: WO2005016244 PAGE: 68 claimed protein
  • 690: PN: WO2004005342 PAGE: 46 claimed protein
  • L-Methioninamide, L-arginyl-L-prolyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-L-phenylalanyl-L-phenylalanylglycyl-L-leucyl-
  • Neurokinin P
  • Substance P (1-11)
  • Substance P (peptide)
  • Substance P (smooth-muscle stimulant)
  • See more synonyms
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