CAS 335161-24-5

AM 2201

Description:

AM 2201 is a synthetic cannabinoid that belongs to a class of compounds designed to mimic the effects of tetrahydrocannabinol (THC), the active component of cannabis. It is characterized by its high affinity for cannabinoid receptors, particularly CB1 and CB2, which are part of the endocannabinoid system in the human body. AM 2201 is known for its potent psychoactive effects, which can include euphoria, altered perception, and relaxation, but it may also lead to adverse effects such as anxiety, paranoia, and increased heart rate. The compound is typically encountered in the form of a white powder or as a component in herbal blends marketed as "spice" or "K2." Due to its synthetic nature and potential for abuse, AM 2201 is often subject to legal restrictions in various jurisdictions. Its safety profile is not well-established, and its use can pose significant health risks, particularly due to the variability in potency and the presence of other harmful substances in products containing synthetic cannabinoids.

Formula: C₂₄H₂₂FNO

InChI: InChI=1S/C24H22FNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2

InChI key: InChIKey=ALQFAGFPQCBPED-UHFFFAOYSA-N

SMILES: C(=O)(C=1C=2C(N(CCCCCF)C1)=CC=CC2)C=3C4=C(C=CC3)C=CC=C4

Synonyms:

• Am 2201
• Jwh 2201
• [1-(5-Fluoropentyl)-1H-Indol-3-Yl]-1-Naphthalenylmethanone
• Methanone, [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-

AM-2201, 1mg/ml in Methanol

Controlled Product

CAS: 335161-24-5

Color and Shape: Single Solution

Ref: LP-JWH-1503-1LM

AM-2201

Controlled Product

CAS: 335161-24-5

Color and Shape: Neat

Ref: LP-JWH-1503-10

AM-2201

Controlled Product

CAS: 335161-24-5

Color and Shape: Neat

Ref: 61-FOR1396.02

AM-2201 ((1-(5-Fluoropentyl)indol-3-yl)(naphthalen-1-yl)methanone) 0.1 mg/ml in Acetonitrile

Controlled Product

CAS: 335161-24-5

Color and Shape: Single Solution

Ref: 61-AMP1396.02-12

AM-2201, 0.1mg/ml in Methanol

Controlled Product

CAS: 335161-24-5

Color and Shape: Single Solution

Ref: LP-JWH-1503-0.1LM

AM-2201 ((1-(5-Fluoropentyl)indol-3-yl)(naphthalen-1-yl)methanone) 1.0 mg/ml in Acetonitrile

Controlled Product

CAS: 335161-24-5

Color and Shape: Single Solution

Ref: 61-AMP1396.02-11

AM-2201

Controlled Product

CAS: 335161-24-5

Applications It is a drug which acts as a potent but unselective agonist for the cannabinoid receptor CB1 or CB2.Synthetic Cannabinoids
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yamada., et al.: J. Med. Chem., 39, 1967 (1996),

Formula: C₂₄H₂₂FNO

Color and Shape: Neat

Molecular weight: 359.44

Ref: TR-A575830

AM-2201-d2

Controlled Product

CAS: 335161-24-5

Formula: C₂₄D₂H₂₀FNO

Color and Shape: Neat

Molecular weight: 361.448

Ref: TR-A575836

AM-2201 (1.0 mg/ml in Methanol)

Controlled Product

CAS: 335161-24-5

Formula: C₂₄H₂₂FNO

Color and Shape: Single Solution

Molecular weight: 359.44

Ref: TR-KIT2205

AM 2201

Controlled Product

CAS: 335161-24-5

AM-2201 is a potent, non-selective synthetic cannabinoid of the aminoalkylindole type which acts as a full agonist at cannabinoid receptors CB1 and CB2 (EC50 = 38 nM and 58 nM, respectively)1. AM-2201 metabolites are also recognised to be full agonists1. Binding to the cannabinoid receptors triggers a reduction of intracellular cAMP levels by inhibiting adenylate cyclase2. In vitro studies have shown 41 and 18 times more affinity for CB1 and CB2 receptors, respectively, when compared to Δ9-THC and revealed dosage-dependent cytotoxicity and chromosomal aberrations in primary cell lines3. Studies on experimental mice models showed bradycardia, hypothermia, and catalepsy1.

Formula: C₂₄H₂₂FNO

Purity: Min. 95%

Molecular weight: 359.44 g/mol

Ref: 3D-FA17340