CAS 33522-95-1

(-)-Noroxymorphone

Description:

(-)-Noroxymorphone is an opioid analgesic that is a derivative of oxymorphone, primarily known for its potent analgesic properties. It is classified as a semi-synthetic opioid and is structurally related to morphine, exhibiting a similar mechanism of action by binding to the mu-opioid receptors in the central nervous system. This compound is characterized by its stereochemistry, specifically the presence of a specific chiral center that contributes to its pharmacological effects. (-)-Noroxymorphone is typically encountered in research settings and is not commonly used in clinical practice due to its potential for abuse and addiction, similar to other opioids. Its pharmacokinetics involve metabolism primarily in the liver, and it may produce effects such as analgesia, sedation, and euphoria, alongside potential side effects like respiratory depression and constipation. Safety and regulatory considerations are paramount due to its classification as a controlled substance in many jurisdictions. Overall, (-)-Noroxymorphone represents a significant compound in the study of opioid pharmacology and its implications in pain management.

Formula:C₁₆H₁₇NO₄

InChI:InChI=1/C16H17NO4/c18-9-2-1-8-7-11-16(20)4-3-10(19)14-15(16,5-6-17-11)12(8)13(9)21-14/h1-2,11,14,17-18,20H,3-7H2/t11-,14+,15+,16-/m1/s1

InChI key:InChIKey=HLMSIZPQBSYUNL-IPOQPSJVSA-N

SMILES:O[C@]12[C@@]34C=5C(O[C@]3(C(=O)CC1)[H])=C(O)C=CC5C[C@]2(NCC4)[H]

Synonyms:

(-)-Noroxymorphone
(5Alpha)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One
(5Beta)-3,14-Dihydroxy-4,5-Epoxymorphinan-6-One
(5alpha)-4,5-Epoxy-3,14-dihydroxymorphinan-6-one
14-Hydroxydihydronormorphinone
7,8-Dihydro-14-hydroxynormorphinone
En 3169
Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-, (5α)-
Morphinan-6-one, 4,5α-epoxy-3,14-dihydroxy-
Normorphinone, 7,8-dihydro-14-hydroxy-
Unii-9Nz7111A9O
(5α)-4,5-Epoxy-3,14-dihydroxymorphinan-6-one
Naloxone Impurity 7（Naloxone EP Impurity A）
Naloxone HCl Impurity
Naltrexone Impurity 6 Monomer
Naltrexone EP Impurity B
LTREXONE HYDROCHLORIDE - IMPURITY B
4,5α-Epoxy-3,14-dihydroxymorphinan-6-one
Naltrexone hydrochloride iMpurity B
(5a)-4,5-Epoxy-3,14-dihydroxy-morphinan-6-one
4-Hydroxydihydronormorphinone
Noroxymorphone hydrochloride solution
Methanol(test NoroxymorphoneHCl,100μg/mLasfreebase)
(4R,4aS,7aR,12bS)-4a,9-dihydroxy-2,3,4,4a,5,6-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7(7aH)-one
Naloxone EP Impurity A
Naltrexone EP Impuirty B
Naloxone Hydrochloride Impurit Ⅰ:(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one
NoroxyMorphone HCl
Naloxone?Hydrochloride EP Impurity A
Nor Oxymorphone (1.0mg/ml in DMSO)
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Purity percentage

100

Brand

Biosynth(1)Standalix(2)TRC(3)

Found 6 products.

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Nor Oxymorphone
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33522-95-1
Applications A metabolite of Naloxone and Naltrexone.
References Cone, E., et al.: Drug Metab. Dispos., 6, 488 (1978), Leow, K., et al.: Ther. Drug Monit., 14, 479 (1992), Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997),
Formula:C₁₆H₁₇NO₄
Color and Shape:Neat
Molecular weight:287.31
Ref: TR-N825300
2500µg
316.00€
VAT not included
25mg
2,125.00€
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Naltrexone impurity B
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33522-95-1
Naltrexone impurity B is an impurity standard for the chemical compound Naltrexone, which is a drug used to treat opioid addiction. It is also a high-purity material for other applications such as pharmaceutical research and development, analytical chemistry, and toxicology studies. Naltrexone impurity B has been synthesized from natural sources and can be custom-synthesized to meet customer requirements. The compound is metabolized in both animals and humans, but the metabolites have not been identified. This product has not been evaluated by the FDA for safety or efficacy.
Formula:C₁₆H₁₇NO₄
Purity:Min. 95 Area-%
Color and Shape:Powder
Molecular weight:287.31 g/mol
Ref: 3D-IN167106
1mg
287.00€
VAT not included
2mg
428.00€
VAT not included
5mg
571.00€
VAT not included
10mg
1,057.00€
VAT not included
25mg
2,368.00€
VAT not included
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Nor Oxymorphone-d5 (major) Hydrochloride
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33522-95-1
Stability Hygroscopic
Applications Nor Oxymorphone-d5 Hydrochloride labelled analogue of Nor Oxymorphone (N825300), a metabolite of Naloxone and Naltrexone.
References Cone, E., et al.: Drug Metab. Dispos., 6, 488 (1978); Leow, K., et al.: Ther. Drug Monit., 14, 479 (1992); Kassahun, K., et al.: Drug Metab. Dispos., 25, 81 (1997)
Formula:C₁₆H₁₂D₅NO₄·HCl
Color and Shape:Neat
Molecular weight:328.8
Ref: TR-N825303
1mg
228.00€
VAT not included
10mg
1,595.00€
VAT not included
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Nor Oxymorphone (1 mg/ml in DMSO)
Controlled ProductPlease note that this is a controlled product in some countries, and needs to be treated in accordance with the relevant regulations. Be aware this might entail additional expenses and documentation.
CAS:
- 33522-95-1
Formula:C₁₆H₁₇NO₄
Color and Shape:Single Solution
Molecular weight:287.31
Ref: TR-KIT0025
1x1ml
946.00€
VAT not included
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Naltrexone EP Impurity B
CAS:
- 33522-95-1
Formula:C₁₆H₁₇NO₄
Molecular weight:287.3
Ref: ST-EA-CP-N57002
10mg
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25mg
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50mg
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100mg
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Naloxone EP Impurity A
CAS:
- 33522-95-1
Formula:C₁₆H₁₇NO₄
Molecular weight:287.32
Ref: ST-EA-CP-N37002
10mg
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25mg
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50mg
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100mg
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