CAS 33543-78-1

Ethyl imidazole-2-carboxylate

Description:

Ethyl imidazole-2-carboxylate is an organic compound characterized by its imidazole ring structure, which is a five-membered aromatic heterocycle containing two nitrogen atoms. This compound features an ethyl ester functional group and a carboxylate moiety, contributing to its reactivity and solubility in various solvents. Ethyl imidazole-2-carboxylate is typically a white to off-white crystalline solid, and it is known for its potential applications in pharmaceuticals and as a building block in organic synthesis. The presence of the imidazole ring imparts unique properties, such as the ability to participate in hydrogen bonding and coordination with metal ions, making it useful in catalysis and coordination chemistry. Additionally, the compound may exhibit biological activity, which can be explored for medicinal chemistry applications. Its stability and reactivity can vary depending on environmental conditions, such as pH and temperature, which are important considerations in its handling and application in research and industry.

Formula: C₆H₈N₂O₂

Synonyms:

• Imidazole-2-carboxylic acid ethyl ester
• RARECHEM AL BI 0666
• 1H-IMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER
• ETHYL IMIDAZOLE-2-CARBOXYLATE
• Ethyl 1H-imidazole-2-carboxylate

Ethyl 2-Imidazolecarboxylate

CAS: 33543-78-1

Formula: C₆H₈N₂O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Yellow to Orange powder to crystal

Molecular weight: 140.14

Ref: 3B-E0952

Ethyl imidazole-2-carboxylate, 97%

CAS: 33543-78-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈N₂O₂

Purity: 97%

Color and Shape: White to yellow or pale cream, Crystalline powder

Molecular weight: 140.14

Ref: 02-L19405

Ethyl 1H-imidazole-2-carboxylate

CAS: 33543-78-1

Formula: C₆H₈N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 140.1399

Ref: IN-DA003QFG

Ethyl 1H-imidazole-2-carboxylate

CAS: 33543-78-1

Ethyl 1H-imidazole-2-carboxylate

Formula: C₆H₈N₂O₂

Purity: ≥95%

Color and Shape: white. crystalline solid

Molecular weight: 140.14g/mol

Ref: 54-OR3003

Ethyl imidazole-2-carboxylate

CAS: 33543-78-1

Formula: C₆H₈N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 140.142

Ref: 10-F078409

Ethyl Imidazole-2-carboxylate

Controlled Product

CAS: 33543-78-1

Applications Ethyl Imidazole-2-carboxylate is an intermediate used to synthesize tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1). It is also used to prepare imidazoindenopyrazinone carboxylic acid derivatives as AMPA antagonists with anticonvulsant activities.
References Miyashiro, J., et al.: Bioorg. Med. Chem. Lett., 19, 4050 (2009); Pratt, J., et al.: Bioorg. Med. Chem. Lett., 10, 2749 (2000)

Formula: C₆H₈N₂O₂

Color and Shape: Neat

Molecular weight: 140.14

Ref: TR-E919195

Ethyl imidazole-2-carboxylate

CAS: 33543-78-1

Ethyl imidazole-2-carboxylate is a β-glucosidase inhibitor that has shown selectivity for cancer cells. This drug inhibits the activity of β-glucosidase, an enzyme that catalyzes the hydrolysis of terminal non-reducing β-D-glucose residues from oligo-, di-, and polysaccharides, which are substrates for glycosylation. Dasatinib is a type of drug that inhibits Bcr-Abl tyrosine kinase and is used in the treatment of chronic myeloid leukemia and other cancers. The inhibition of this enzyme may lead to increased levels of thymidine (a nucleotide) and therefore, DNA synthesis. Dasatinib also blocks the function of ribonucleotide reductases, which are enzymes that reduce ribonucleotides to deoxyribonucleotides. This mechanism prevents DNA replication by inhibiting the production of new DNA

Purity: Min. 95%

Ref: 3D-FE44026