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CAS 336-45-8

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(9xi,11beta)-9-fluoro-11,21-dihydroxypregn-4-ene-3,20-dione

Description:
The chemical substance known as (9xi,11beta)-9-fluoro-11,21-dihydroxypregn-4-ene-3,20-dione, with the CAS number 336-45-8, is a synthetic corticosteroid commonly referred to as dexamethasone. It is characterized by its potent anti-inflammatory and immunosuppressive properties, making it widely used in medical applications to treat various conditions, including allergies, autoimmune diseases, and certain types of cancer. Dexamethasone is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its molecular structure features a fluorine atom at the 9-position and hydroxyl groups at the 11 and 21 positions, which contribute to its biological activity. The compound acts primarily by binding to glucocorticoid receptors, influencing gene expression and modulating inflammatory responses. Due to its efficacy, dexamethasone is often administered in various forms, including oral tablets, injections, and topical formulations, depending on the therapeutic needs. However, it is essential to use this medication under medical supervision due to potential side effects associated with corticosteroid therapy.
Formula:C21H29FO4
InChI:InChI=1/C21H29FO4/c1-19-10-18(26)21(22)15(14(19)5-6-16(19)17(25)11-23)4-3-12-9-13(24)7-8-20(12,21)2/h9,14-16,18,23,26H,3-8,10-11H2,1-2H3/t14-,15-,16+,18-,19-,20-,21?/m0/s1
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Found 1 products.
  • (8S,10S,11S,13S,14S,17S)-9-Fluoro-11-Hydroxy-17-(2-Hydroxyacetyl)-10,13-Dimethyl-2,6,7,8,11,12,14,…
    Biosynth
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    (8S,10S,11S,13S,14S,17S)-9-Fluoro-11-Hydroxy-17-(2-Hydroxyacetyl)-10,13-Dimethyl-2,6,7,8,11,12,14,15,16,17-Decahydro-1H-Cyclopenta[a ]Phenanthren-3-One

    Controlled Product
    CAS:
    (8S,10S,11S,13S,14S,17S)-9-Fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one (fluorometholone) is a corticosteroid that is used in the treatment of asthma and other respiratory diseases. Fluorometholone has been shown to have strong antiinflammatory activity and inhibit the production of inflammatory cytokines. It also has mineralocorticoid activity and can be used to treat adrenal insufficiency. This drug has potent potencies structurally similar to glucocorticoids and mineralocorticoids.
    Formula:C21H29FO4
    Purity:Min. 95%
    Molecular weight:364.45 g/mol

    Ref: 3D-FF104053

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