CAS 336115-72-1

SB-743921

Description:

SB-743921, with the CAS number 336115-72-1, is a small molecule that has been investigated primarily for its potential as an anti-cancer agent. It functions as a selective inhibitor of certain kinases, particularly those involved in cell signaling pathways that regulate cell proliferation and survival. This compound has shown promise in preclinical studies for its ability to induce apoptosis in cancer cells and inhibit tumor growth. Its mechanism of action typically involves the disruption of specific protein interactions and signaling cascades that are crucial for cancer cell viability. Additionally, SB-743921 has been characterized by its moderate solubility in organic solvents and its stability under physiological conditions, making it a candidate for further development in therapeutic applications. As with many investigational drugs, ongoing research is necessary to fully elucidate its pharmacokinetics, efficacy, and safety profile in clinical settings.

Formula: C₃₀H₃₂BrClN₄O₂

InChI: InChI=1/C30H32BrClN4O2/c1-4-27(35(18-8-17-34(2)3)29(37)22-11-13-23(31)14-12-22)28-33-26-19-24(32)15-16-25(26)30(38)36(28)20-21-9-6-5-7-10-21/h5-7,9-16,19,27H,4,8,17-18,20H2,1-3H3

Synonyms:

• N-[1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl]-4-bromo-N-[3-(dimethylamino)propyl]benzamide
• Benzamide, 4-bromo-N-[1-[7-chloro-3,4-dihydro-4-oxo-3-(phenylmethyl)-2-quinazolinyl]propyl]-N-[3-(dimethylamino)propyl]-
• CK0106023

N-(1-(3-Benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide

CAS: 336115-72-1

This is a research tool that can be used to study the activation of receptors or ion channels. It is a ligand that binds to the receptor and activates it. The chemical structure of this compound is N-(1-(3-benzyl-7-chloro-4-oxo-3,4-dihydroquinazolin-2-yl)propyl)-4-bromo-N-(3-(dimethylamino)propyl)benzamide. This chemical has been shown to inhibit the activity of ion channels by binding to them and blocking their function.

Formula: C₃₀H₃₂BrClN₄O₂

Purity: Min. 95%

Molecular weight: 596 g/mol

Ref: 3D-LNA11572

CK0106023

CAS: 336115-72-1

CK0106023, a KSP inhibitor, shows strong antitumor effects in mice, outperforming paclitaxel, and induces monopolar spindles.

Formula: C₃₀H₃₂BrClN₄O₂

Color and Shape: Solid

Molecular weight: 595.96

Ref: TM-T69415