CAS 336615-64-6

5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-pentyl-1H-pyrazole-3-carboxamide

Description:

5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-pentyl-1H-pyrazole-3-carboxamide, with the CAS number 336615-64-6, is a synthetic organic compound that belongs to the class of pyrazole derivatives. This compound features a pyrazole ring, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of multiple chlorophenyl groups indicates significant halogenation, which can influence its biological activity and lipophilicity. The pentyl group contributes to the compound's hydrophobic characteristics, potentially affecting its solubility and permeability in biological systems. The carboxamide functional group suggests that it may engage in hydrogen bonding, which can be crucial for its interaction with biological targets. Overall, this compound may exhibit interesting pharmacological properties, making it a subject of interest in medicinal chemistry and drug development. Its specific characteristics, such as melting point, solubility, and biological activity, would require empirical data for precise evaluation.

Formula: C₂₂H₂₂Cl₃N₃O

InChI: InChI=1S/C22H22Cl3N3O/c1-3-4-5-12-26-22(29)20-14(2)21(15-6-8-16(23)9-7-15)28(27-20)19-11-10-17(24)13-18(19)25/h6-11,13H,3-5,12H2,1-2H3,(H,26,29)

InChI key: InChIKey=JDBOTXIRNSWBCG-UHFFFAOYSA-N

SMILES: CC1=C(N(N=C1C(NCCCCC)=O)C2=C(Cl)C=C(Cl)C=C2)C3=CC=C(Cl)C=C3

Synonyms:

• O 1269
• 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-pentyl-1H-pyrazole-3-carboxamide
• 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-pentyl-

O-1269

CAS: 336615-64-6

O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.

Formula: C₂₂H₂₂Cl₃N₃O

Color and Shape: Solid

Molecular weight: 450.79

Ref: TM-T201557