CAS 33671-37-3

5-(2-chlorophenyl)-7-ethyl-2,4-dihydro-3H-thieno[2,3-e][1,4]diazepin-3-one

Description:

5-(2-Chlorophenyl)-7-ethyl-2,4-dihydro-3H-thieno[2,3-e][1,4]diazepin-3-one is a chemical compound characterized by its unique thieno-diazepine structure, which incorporates a thieno ring fused to a diazepine moiety. This compound features a 2-chlorophenyl substituent and an ethyl group, contributing to its distinct chemical properties. The presence of the thieno ring suggests potential biological activity, as thieno derivatives are often explored for their pharmacological effects. The compound's structure includes a carbonyl group, which may influence its reactivity and interactions with biological targets. It is typically synthesized through multi-step organic reactions, and its properties may include moderate solubility in organic solvents and potential stability under standard laboratory conditions. As with many diazepine derivatives, it may exhibit psychoactive or therapeutic effects, making it of interest in medicinal chemistry. However, specific data regarding its toxicity, pharmacokinetics, and detailed biological activity would require further investigation through empirical studies.

Formula: C₁₅H₁₃ClN₂OS

InChI: InChI=1/C15H13ClN2OS/c1-2-9-7-11-14(10-5-3-4-6-12(10)16)18-13(19)8-17-15(11)20-9/h3-7H,2,8H2,1H3,(H,18,19)

SMILES: CCc1cc2=C(c3ccccc3Cl)N=C(CN=c2s1)O

N-Desmethyl clotiazepam

CAS: 33671-37-3

N-Desmethyl clotiazepam (Desmethylclotiazepam) is an active metabolite of Clotiazepam.

Formula: C₁₅H₁₃ClN₂OS

Color and Shape: Solid

Molecular weight: 304.8

Ref: TM-T203043

N-Desmethyl Clotiazepam

Controlled Product

CAS: 33671-37-3

Applications Clotiazepam (C587410) metabolite, with central nervous depressant and anxiolytic activity.
References Ito, K. et al.: Biopharm. Drug. Dispos., 18, 293 (1997); Nakanishi, M. et al.: J. Med. Chem., 16, 214 (1973)

Formula: C₁₅H₁₃ClN₂OS

Color and Shape: Neat

Molecular weight: 304.79

Ref: TR-D291535

N-Desmethyl clotiazepam

Controlled Product

CAS: 33671-37-3

N-Desmethyl clotiazepam is a potent inhibitor of the GABA receptor, which belongs to the class of ligands and is an antagonist. N-Desmethyl clotiazepam binds to the interface of the GABA receptor and blocks the opening of chloride channels, preventing chloride ions from entering into cells. This drug can be used as a research tool in cell biology and pharmacology to study how proteins interact with each other. It has been shown to be a high-purity reagent that can be used in life science applications such as ion channel research, protein interactions, and receptor binding studies.

Formula: C₁₅H₁₃ClN₂OS

Purity: Min. 95%

Molecular weight: 304.8 g/mol

Ref: 3D-IBA67137