CymitQuimica logo

CAS 336881-26-6

:

Uridine,2'-deoxy-2'-fluoro-5-(trimethylstannyl)- (9CI)

Description:
Uridine, 2'-deoxy-2'-fluoro-5-(trimethylstannyl)-, with the CAS number 336881-26-6, is a modified nucleoside that features a fluorine atom at the 2' position and a trimethylstannyl group at the 5' position. This compound is characterized by its structural modifications that enhance its stability and bioactivity compared to natural nucleosides. The presence of the fluorine atom can influence the compound's interaction with nucleic acids and enzymes, potentially affecting its incorporation into RNA or DNA. The trimethylstannyl group is often utilized in synthetic chemistry for its ability to facilitate various reactions, including coupling reactions in the synthesis of oligonucleotides. This compound may be of interest in research areas such as medicinal chemistry, molecular biology, and the development of antiviral agents, as modified nucleosides can exhibit unique pharmacological properties. Overall, the unique structural features of this compound contribute to its potential applications in scientific research and therapeutic development.
Formula:C12H19FN2O5Sn
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
  • 2''-Deoxy-2''-fluoro-5-(trimethylstannyl)uridine-epimer
    Glentham
    + Info

    2''-Deoxy-2''-fluoro-5-(trimethylstannyl)uridine-epimer

    CAS:

    Ref: 7W-GN6371

    ne
    To inquire
  • 2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer
    Biosynth
    + Info

    2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer

    CAS:
    2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer is a novel nucleoside that is synthesized by the chemical reaction of 2'-deoxy-5-(trimethylstannyl)uridine and 5-bromo-2'-deoxyuridine. It is a nucleotide analogue that acts as a DNA phosphoramidite in solid phase synthesis. This compound has antiviral, anticancer, and antiviral properties. It can be used to activate ribonucleotides or deoxyribonucleotides for incorporation into DNA or RNA. 2'-Deoxy-2'-fluoro-5-(trimethylstannyl)uridine-epimer has shown good cytotoxicity against leukemia cells, lymphoma cells, and other tumor cells in vitro. This may be due to its ability to inhibit protein synthesis by blocking the enzyme ribonuclease H (RNase H
    Formula:C12H19FN2O5Sn
    Purity:Min. 95%
    Molecular weight:408.98 g/mol

    Ref: 3D-ND03507

    ne
    To inquire