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CAS 33737-08-5

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1,2-O-Isopropylidene-6-O-trityl-α-D-glucofuranose

Description:
1,2-O-Isopropylidene-6-O-trityl-α-D-glucofuranose is a glycoside derivative of glucose, characterized by its protective groups that enhance its stability and reactivity in synthetic applications. The isopropylidene group at the 1 and 2 positions serves to protect the hydroxyl groups, while the trityl group at the 6 position provides additional protection and increases lipophilicity, facilitating purification and handling. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents like dichloromethane and methanol, but less so in water due to its hydrophobic trityl group. It is commonly used in carbohydrate chemistry for the synthesis of more complex glycosides and oligosaccharides, as the protective groups can be selectively removed under mild conditions. The compound's structure allows for specific reactivity patterns, making it valuable in the development of glycosylation reactions and other carbohydrate-based synthetic methodologies. As with many glycosides, it is important to handle this compound with care, following appropriate safety protocols.
Formula:C28H30O6
Synonyms:
  • 1,2-O-Isopropylidene-6-O-trityl-α-D-glucofuranose
  • α-D-Glucofuranose, 1,2-O-(1-methylethylidene)-6-O-(triphenylmethyl)-
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