CAS 33754-49-3

Zolazepam hydrochloride

Description:

Zolazepam hydrochloride is a pharmaceutical compound classified as a benzodiazepine derivative, primarily used for its anxiolytic and sedative properties. It is often utilized in veterinary medicine, particularly for its tranquilizing effects in animals. The substance acts on the central nervous system by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), leading to increased sedation and reduced anxiety. Zolazepam hydrochloride is typically administered in a hydrochloride salt form, which enhances its solubility in water, facilitating easier administration. The compound is characterized by its relatively rapid onset of action and a duration of effect that can vary based on dosage and individual metabolism. As with other benzodiazepines, potential side effects may include drowsiness, ataxia, and, in some cases, dependence with prolonged use. It is important to use zolazepam under veterinary supervision to ensure appropriate dosing and to monitor for any adverse reactions.

Formula: C₁₅H₁₅FN₄O·ClH

InChI: InChI=1S/C15H15FN4O.ClH/c1-9-13-14(10-6-4-5-7-11(10)16)17-8-12(21)19(2)15(13)20(3)18-9;/h4-7H,8H2,1-3H3;1H

InChI key: InChIKey=NJERAXSSDSHLGE-UHFFFAOYSA-N

SMILES: CC=1C=2C(=NCC(=O)N(C)C2N(C)N1)C3=C(F)C=CC=C3.Cl

Synonyms:

• 4-(2-fluorophenyl)-1,3,8-trimethyl-6,8-dihydropyrazolo[3,4-e][1,4]diazepin-7(1H)-one hydrochloride (1:1)
• 4-(o-Fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo(3,4-e)(1,4)diazepin-7(1H)-one monohydrochloride
• Ci 716
• Pyrazolo(3,4-e)(1,4)diazepin-7(1H)-one, 4-(2-fluorophenyl)-6,8-dihydro-1,3,8-trimethyl-, monohydrochloride
• Pyrazolo[3,4-e][1,4]diazepin-7(1H)-one, 4-(2-fluorophenyl)-6,8-dihydro-1,3,8-trimethyl-, hydrochloride (1:1)
• Telazol
• Unii-45Sj093Q1N
• Zolazepam HCl
• Zolazepam hydrochloride
• Zolazepam hydrochloride [USAN]
• 4-(2-Fluorophenyl)-6,8-dihydro-1,3,8-trimethylpyrazolo(3,4-e)(1,4)diazepin-7(1H)-one monohydrochloride

Zolazepam Hydrochloride

CAS: 33754-49-3

Anticonvulsants, hypnotics and sedatives

Formula: C₁₅H₁₅FN₄O·HCl

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 322.09967

Ref: 45-1724805

Zolazepam Hydrochloride

Controlled Product

CAS: 33754-49-3

Applications A sedative and anesthetic agent.
References Winters, W., et al.: Neuropharmacology, 11, 303 (1972), Genevois, J., et al.: Rec. Med. Vet.,164, 289 (1988),

Formula: C₁₅H₁₅FN₄O·ClH

Color and Shape: Neat

Molecular weight: 322.77

Ref: TR-Z613500

Zolazepam hydrochloride

Controlled Product

CAS: 33754-49-3

Zolazepam is a benzodiazepine that has antinociceptive properties and is used as an anesthetic. The effective dose of zolazepam in humans is 5-10 mg intravenously, with a maximum dose of 25 mg. Zolazepam has been found to have no effect on systolic blood pressure or heart rate, but does cause significant reduction in terminal half-life. Zolazepam's antinociceptive effects are mediated through the inhibition of calcium ion channels, which results in decreased neuronal activity in the spinal cord and brainstem. Zolazepam causes sedation and immobilization by suppressing the function of neurons that control skeletal muscles. Zolazepam also has been shown to inhibit osteoclast formation, which may be beneficial for patients with metabolic bone diseases such as Paget's disease or osteoporosis.

Purity: Min. 95%

Ref: 3D-FZ61533