CAS 33755-53-2

d-Biotin p-nitrophenyl ester

Description:

d-Biotin p-nitrophenyl ester, with the CAS number 33755-53-2, is a derivative of biotin, a water-soluble B-vitamin that plays a crucial role in various metabolic processes, particularly in the metabolism of fats, carbohydrates, and proteins. This compound features a p-nitrophenyl ester group, which enhances its reactivity and solubility in organic solvents, making it useful in biochemical applications, particularly in the field of bioconjugation and labeling. The presence of the p-nitrophenyl group allows for easy detection and quantification due to its chromogenic properties. d-Biotin itself is known for its ability to bind to avidin and streptavidin with high affinity, which is leveraged in various biochemical assays and purification techniques. The esterification of biotin with p-nitrophenol modifies its properties, potentially influencing its interaction with biological molecules. Overall, d-Biotin p-nitrophenyl ester serves as a valuable tool in molecular biology and biochemistry for studying protein interactions and facilitating the development of bioconjugates.

Formula: C₁₆H₁₉N₃O₅S

InChI: InChI=1/C16H19N3O5S/c20-14(24-11-7-5-10(6-8-11)19(22)23)4-2-1-3-13-15-12(9-25-13)17-16(21)18-15/h5-8,12-13,15H,1-4,9H2,(H2,17,18,21)/t12-,13-,15-/m0/s1

SMILES: C(CCC(=O)Oc1ccc(cc1)N(=O)=O)C[C@H]1[C@@H]2[C@H](CS1)N=C(N2)O

Synonyms:

• BNP
• 4-nitrophenyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate
• HTIB [Hydroxy(tosyloxy)iodo]benzene
• Biotin-ONP

(+)-Biotin 4-Nitrophenyl Ester

CAS: 33755-53-2

Formula: C₁₆H₁₉N₃O₅S

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 365.40

Ref: 3B-B4009

(+)-Biotin 4-Nitrophenyl Ester

CAS: 33755-53-2

Formula: C₁₆H₁₉N₃O₅S

Purity: 97%

Color and Shape: Solid

Molecular weight: 365.4042

Ref: IN-DA007ITM

4-Nitrophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

CAS: 33755-53-2

4-Nitrophenyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate

Purity: 98%

Molecular weight: 365.40g/mol

Ref: 54-OR1011632

(+)-Biotin-ONP

CAS: 33755-53-2

(+)-Biotin-ONP

Purity: ≥98%

Molecular weight: 365.4g/mol

Ref: 54-BUP17905

Biotin p-nitrophenyl ester

CAS: 33755-53-2

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 365.3999938964844

Ref: 10-F493609

D-Biotin p-nitrophenyl ester

CAS: 33755-53-2

Ref: 7W-GW9462

(+)-Biotin-ONP

CAS: 33755-53-2

(+)-Biotin-ONP ((+)-Biotin 4-nitrophenyl ester) is an alkyl chain-based PROTAC linker. (+)-Biotin-ONP can be used in the synthesis of PROTACs.

Formula: C₁₆H₁₉N₃O₅S

Purity: 99.91%

Color and Shape: Solid

Molecular weight: 365.4

Ref: TM-T18546

(+)-Biotin-ONP

Controlled Product

CAS: 33755-53-2

Applications D-Biotin 4-Ntrophenyl Ester, can be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies.
References Chia-Ho Chu et. al; Scientific reports, 7(1), undefined (2017-7-14);

Formula: C₁₆H₁₉N₃O₅S

Color and Shape: Neat

Molecular weight: 365.4

Ref: TR-B391605

BIotin-ONp

CAS: 33755-53-2

Biotin-ONp is a monoclonal antibody that binds to uptake and efflux pump proteins. It is a conjugate of biotin and an oligonucleotide containing a carboxy terminal peptide. This antibody has been used as a model system for the study of peptide hormones and their reaction products. Biotin-ONp has also been used as an analytical chemistry reagent for the determination of growth factors in serum, and for the detection of antibodies in immunoassays using magnetic particles.

Formula: C₁₆H₁₉N₃O₅S

Purity: Min. 95%

Molecular weight: 365.41 g/mol

Ref: 3D-BDN-6004-PI