CAS 338-98-7

Isoflupredone acetate

Description:

Isoflupredone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is characterized by its ability to modulate the immune response and reduce inflammation, making it useful in various therapeutic applications, particularly in dermatology and veterinary medicine. The compound is typically administered topically or via injection, depending on the condition being treated. Isoflupredone acetate exhibits a high affinity for glucocorticoid receptors, which contributes to its efficacy in managing conditions such as dermatitis, allergies, and certain autoimmune disorders. Its chemical structure includes a steroid backbone, which is common among corticosteroids, and it is known for its relatively low systemic absorption when applied topically, minimizing potential side effects. The substance is also recognized for its stability and solubility in various solvents, which facilitates its formulation in pharmaceutical products. As with all corticosteroids, careful consideration of dosage and duration of use is essential to avoid potential adverse effects, such as skin thinning or systemic absorption leading to hormonal imbalances.

Formula: C₂₃H₂₉FO₆

InChI: InChI=1S/C23H29FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h6,8,10,16-18,27,29H,4-5,7,9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1

InChI key: InChIKey=ZOCUOMKMBMEYQV-GSLJADNHSA-N

SMILES: F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(COC(C)=O)=O)(O)CC3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]

Synonyms:

• (11Beta)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxypregna-1,4-diene-3,20-dione
• (8Xi,10Xi,11Beta,13Xi,14Xi,17Xi)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 21-Acetoxy-9-Fluoro-11B,17-Dihydroxypregna-1,4-Diene-3,20-Dione
• 9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 9-Fluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
• 9-Fluoroprednisolone 21-acetate
• 9-Fluoroprednisolone acetate
• 9α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate
• 9α-Fluoroprednisolone 21-acetate
• 9α-Fluoroprednisolone acetate
• Isoflupredone  acetate
• NSC 12600
• NSC 37977
• Predef
• Predef R 2X
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-, 21-acetate

Isoflupredone Acetate

CAS: 338-98-7

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₃H₂₉FO₆

Color and Shape: White Powder

Molecular weight: 420.19482

Ref: 45-1348907

21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-diene-3,20-dione

CAS: 338-98-7

Formula: C₂₃H₂₉FO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 420.4712

Ref: IN-DA00BXRV

Isoflupredone Acetate

CAS: 338-98-7

Formula: C₂₃H₂₉FO₆

Color and Shape: Off-White Solid

Molecular weight: 420.48

Ref: 4Z-I-082001

Isoflupredone acetate

CAS: 338-98-7

Formula: C₂₃H₂₉FO₆

Purity: ≤ 1.0%

Color and Shape: White to almost white powder

Molecular weight: 420.47

Ref: 7W-GP0734

Isoflupredone Acetate

CAS: 338-98-7

Isoflupredone Acetate

Purity: ≥98%

Molecular weight: 420.47g/mol

Ref: 54-BUP11955

Isoflupredone Acetate

CAS: 338-98-7

Isoflupredone Acetate is a corticosteroid with the activity of topical anti-inflammatory.

Formula: C₂₃H₂₉FO₆

Purity: 99.43%

Color and Shape: Solid

Molecular weight: 420.47

Ref: TM-T21193

Isoflupredone Acetate

Controlled Product

CAS: 338-98-7

Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.
References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);

Formula: C₂₃H₂₉FO₆

Color and Shape: Off-White

Molecular weight: 420.47

Ref: TR-I816610

Isoflupredone Acetate

CAS: 338-98-7

Formula: C₂₃H₂₉FO₆

Molecular weight: 420.48

Ref: ST-EA-CP-B25022

Isoflupredone acetate

Controlled Product

CAS: 338-98-7

Isoflupredone acetate is a synthetic corticosteroid that has been used in the treatment of inflammatory diseases, such as rheumatoid arthritis and asthma. This drug binds to the glucocorticoid receptor, blocking steroidogenesis and thus inhibiting the production of cortisol. Isoflupredone acetate can be detected in urine samples for up to 4 days after administration. Preparations containing this drug are often taken in tablet form with sodium succinate as a stabilizer. The sample preparation process involves dissolving the tablet in an acid solution, which releases the active ingredient into solution so it can be analyzed by GC-MS or LC-MS/MS. Isoflupredone acetate has been shown to increase energy expenditure and reduce body weight gain in rats with experimentally induced diabetes mellitus.

Formula: C₂₃H₂₉FO₆

Purity: Min. 95%

Molecular weight: 420.47 g/mol

Ref: 3D-FI24677