CAS 3380-34-5

Triclosan

Description:

Triclosan, with the CAS number 3380-34-5, is an antimicrobial agent commonly used in various consumer products, including soaps, toothpaste, and household items, due to its ability to inhibit bacterial growth. It is a synthetic compound belonging to the class of chlorinated aromatic compounds, characterized by its white crystalline solid form at room temperature. Triclosan is lipophilic, which allows it to penetrate cell membranes, disrupting bacterial fatty acid synthesis. Its chemical formula is C12H7Cl3O2, and it has a molecular weight of approximately 289.5 g/mol. Triclosan exhibits broad-spectrum antimicrobial activity against a range of bacteria and fungi, making it effective in preventing infections. However, its widespread use has raised concerns regarding environmental persistence, potential endocrine-disrupting effects, and the development of antibiotic-resistant bacteria. Regulatory agencies have scrutinized its safety, leading to restrictions in certain applications. Overall, while triclosan serves as an effective antimicrobial agent, its environmental and health implications necessitate careful consideration in its use and regulation.

Formula: C₁₂H₇Cl₃O₂

InChI: InChI=1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H

InChI key: InChIKey=XEFQLINVKFYRCS-UHFFFAOYSA-N

SMILES: O(C1=C(Cl)C=C(Cl)C=C1)C2=C(O)C=C(Cl)C=C2

Synonyms:

• 2',4',4-Trichloro-2-hydroxydiphenyl ether
• 2',4',4-Trichloro-2-hydroxydiphenylether
• 2',4,4'-Trichloro-2-hydroxydiphenyl ether
• 2'-Hydroxy-2,4,4'-Trichloro-Phenylethe
• 2'-Hydroxy-2,4,4'-trichlorodiphenyl ether
• 2,2'-Oxybis(1',5'-dichlorophenyl-5-chlorophenol)
• 2,2′-Oxybis(1′,5′-dichlorophenyl-5-chlorophenol)
• 2,4,4'-Trichlorine-2'-Hydroxyl Diphenyl Ether
• 2,4,4'-Trichlorine-2'-Hydroxyl Diphenyl Ethyl
• 2,4,4'-Trichloro-2'-Hydroxy Diphenylether
• 2,4,4'-Trichloro-2'-hydroxyldiphenyl ether
• 2,4,4-Trichloro-2-hydroxydiphenyl ether
• 2-(2,4-Dichlorophenoxy)-5-chlorophenol
• 2-Hydroxy-2',4,4'-trichlorodiphenyl ether
• 3-Chloro-6-(2,4-dichlorophenoxy)phenol
• 4-Chloro-2-hydroxyphenyl 2,4-dichlorophenyl ether
• 4-Chloro-2-hydroxyphenyl2,4-dichlorophenyl ether
• 5-Chloro-2-(2', 4'-dichlorophenoxy) phenol
• 5-Chloro-2-(2,4-Dichlorophenoxy)-Pheno2,4,4-Trichloro-2-Hydroxydiphenylether(Irgasandp-300)
• 5-Chloro-2-(2,4-dichlorophenoxy) phen
• 5-Chloro-2-(2,4-dichlorophenoxy)phenol
• Anvasan AM 110
• Anvasan AM 110 new
• Aquasept
• Bacti-Stat soap
• Cansan TCH
• Ch 3565
• Ch 3635
• Ch3565
• Cloxifenol
• Diphenyl Ether, 2,4,4'-Trichloro-2'-Hydroxy-
• Dp 300
• Dp300
• Ether,2'-Hydroxy-2,4,4'-Trichlorodiphenyl
• Gamophen
• Germicide CA
• Invasan
• Invasan DP 300R
• Irgacare-MP
• Irgacide LP 10
• Irgaguard B 1000
• Irgaguard B 1325
• Irgasan
• Irgasan CH 3565
• Irgasan DP 30
• Irgasan DP 300
• Irgasan DP 3000
• Irgasan DP 400
• Irgasan PE 30
• Irgasan PG 60
• Irgasandp300
• Microban
• Microban Additive B
• Microban B
• Microfresh 9200-200
• Microfresh Liquid Formulation 9200-200
• Nm 100
• Oletron
• Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-, dihydrogen phosphate
• Phenol,5-chloro-2-(2,4-dichlorophenoxy)-
• Sanitized XTX
• Sapoderm
• SterZac
• Tccp
• Thdp
• Tinosan AM 100
• Tinosan AM 110
• Triclosam
• Triclosan(USP 30)
• Ultra-Fresh NM 100
• Ultra-Fresh NM-V 2
• Ultrafresh NM-V 2
• Vinyzene DP 7000
• Yujiexin
• Zilesan UW

Triclosan

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 289.54

Ref: 3B-T1872

5-Chloro-2-(2,4-dichlorophenoxy)phenol, 99%

CAS: 3380-34-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₂H₇Cl₃O₂

Purity: 99%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 289.54

Ref: 02-L18655

Triclosan

CAS: 3380-34-5

Ether-phenols, ether-alcohol-phenols and their halogenated, sulfonated, nitrated or nitrosated derivatives

Formula: C₁₂H₇Cl₃O₂

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 287.95116

Ref: 45-1682206

5-Chloro-2-(2,4-Dichlorophenoxy)Phenol

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 289.5418

Ref: IN-DA00348R

Triclosan

CAS: 3380-34-5

Triclosan (Irgasan) is an antibacterial and antifungal agent.

Formula: C₁₂H₇Cl₃O₂

Purity: 99.63%

Color and Shape: White Solid Crystalline

Molecular weight: 289.54

Ref: TM-T1314

Triclosan

CAS: 3380-34-5

Triclosan

Purity: ≥98%

Molecular weight: 289.54g/mol

Ref: 54-BUP14852

Triclosan

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Purity: ≥ 98.0%

Color and Shape: White crystalline powder or crystals

Molecular weight: 289.55

Ref: 7W-GA5716

Triclosan

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Molecular weight: 289.54

Ref: 4Z-T-302

Triclosan, USP grade

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Purity: ≤ 0.1%

Color and Shape: White crystalline powder or crystals

Molecular weight: 289.55

Ref: 7W-GP4689

Triclosan

CAS: 3380-34-5

Color and Shape: Neat

Ref: 86-MM0610.00

Pharmaceuticals Mixture 327 200 µg/mL in Methanol

Controlled Product

CAS: 15687-27-1, 22204-53-1, 25812-30-0, 3380-34-5

Color and Shape: Mixture

Ref: 04-A50000327ME

Triclosan 10 µg/mL in Cyclohexane

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Color and Shape: Single Solution

Molecular weight: 289.54

Ref: 04-L17803000CY

Triclosan

Controlled Product

CAS: 3380-34-5

Formula: C₁₂H₇Cl₃O₂

Color and Shape: Neat

Molecular weight: 289.54

Ref: 04-C17803000

Irgasan

CAS: 3380-34-5

Irgasan

Formula: C₁₂H₇Cl₃O₂

Purity: 98%

Color and Shape: white crystalline powder

Molecular weight: 289.54g/mol

Ref: 54-BII1002

Triclosan

CAS: 3380-34-5

Applications Triclosan is used as bactericide and preservative for cosmetic and detergent compositions (1). Broadly used as an antiseptic and disinfectant (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Lindström, A. et al.: Environ. Sci. Technol. 2002 Jun 1;36(11):2322-9. 2. Ruszkiewicz, J. et al.: J. Toxicol. Environ. Health B. Crit. Rev. 2017;20(2):104-117.

Formula: C₁₂H₇Cl₃O₂

Color and Shape: Neat

Molecular weight: 289.54

Ref: TR-T774250

Triclosan-13C6

Controlled Product

CAS: 3380-34-5

Applications Isotope labelled Triclosan is used as bactericide and preservative for cosmetic and detergent compositions (1). Broadly used as an antiseptic and disinfectant (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Lindström, A. et al.: Environ. Sci. Technol. 2002 Jun 1;36(11):2322-9. 2. Ruszkiewicz, J. et al.: J. Toxicol. Environ. Health B. Crit. Rev. 2017;20(2):104-117.

Formula: C₆₁₃C₆H₇Cl₃O₂

Color and Shape: White

Molecular weight: 295.5

Ref: TR-T774253

Trichlorosan

CAS: 3380-34-5

Trichlorosan is a biocide that is used as a disinfectant and preservative, and has also been shown to have antibacterial properties. It is often used in industrial settings to inhibit the growth of bacteria in process water, cooling towers, and wastewater treatment systems. Trichlorosan has been shown to be genotoxic in rats at high doses. This chemical can be found in personal care products such as soaps, toothpaste, mouthwash, deodorants, or body lotion. It can also be found in some household items such as kitchenware, clothes and bedding. Triclosan is one of the active ingredients in trichlorosan that prevents bacterial growth by binding to the enzyme that catalyzes the conversion of glycerol to fatty acids and lysing cells through cell membrane disruption. The enzyme activity index for triclosan was determined by measuring the amount of time it takes for a solution containing benzalkonium chloride (B

Formula: C₁₂H₇Cl₃O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 289.54 g/mol

Ref: 3D-FT02357