2-(Hydroxymethyl)benzamide, with the CAS number 33832-98-3, is an organic compound characterized by the presence of both an amide and a hydroxymethyl functional group attached to a benzene ring. This compound features a benzene ring substituted at the second position with a hydroxymethyl group (-CH2OH) and an amide group (-C(=O)NH2) at the first position. It is typically a white to off-white solid at room temperature and is soluble in polar solvents due to the presence of the hydroxymethyl and amide functionalities. The compound exhibits properties typical of amides, such as the ability to participate in hydrogen bonding, which can influence its solubility and reactivity. It may be used in various chemical syntheses and research applications, particularly in the fields of medicinal chemistry and organic synthesis. Safety data should be consulted for handling and storage, as with any chemical substance.

2-(Hydroxymethyl)benzamide

33832-98-3: 2-(Hydroxymethyl)benzamide, with the CAS number 33832-98-3, is an organic compound characterized by the presence of both an amide and a hydroxymethyl functional group attached to a benzene ring. This compound features a benzene ring substituted at the second position with a hydroxymethyl group (-CH2OH) and an amide group (-C(=O)NH2) at the first position. It is typically a white to off-white solid at room temperature and is soluble in polar solvents due to the presence of the hydroxymethyl and amide functionalities. The compound exhibits properties typical of amides, such as the ability to participate in hydrogen bonding, which can influence its solubility and reactivity. It may be used in various chemical syntheses and research applications, particularly in the fields of medicinal chemistry and organic synthesis. Safety data should be consulted for handling and storage, as with any chemical substance.

<p>2-(Hydroxymethyl)benzamide is an analog of 2,4-diaminotoluene that has been shown to have neuroprotective and anti-apoptotic properties. It has been shown to protect human liver cells against cytotoxic effects of acetaminophen, which may be due to its ability to activate the phosphatidylinositol 3-kinase/Akt pathway. In addition, 2-(Hydroxymethyl)benzamide inhibits the proliferation of Ba/F3 cells by inducing apoptosis. The compound has also been found in urine samples as a metabolite of benzoic acid. This product can be synthesized in an asymmetric manner by reacting 2,4-diaminotoluene with potassium tert-butoxide and formaldehyde.</p>

CAS 33832-98-3

2-(Hydroxymethyl)benzamide

2-(Hydroxymethyl)benzamide

Ref: 3D-IBA83298