CAS 338404-52-7

6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime

Description:

6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime, with CAS number 338404-52-7, is a synthetic organic compound characterized by its complex structure, which includes an imidazole ring fused to a thiazole moiety. This compound features a carboxaldehyde functional group and an oxime derivative, which contributes to its reactivity and potential biological activity. The presence of chlorophenyl groups enhances its lipophilicity and may influence its interaction with biological targets. Typically, compounds of this nature are investigated for their pharmacological properties, including antimicrobial, anticancer, or anti-inflammatory activities. The specific arrangement of substituents on the aromatic rings can significantly affect the compound's solubility, stability, and overall biological efficacy. As with many heterocyclic compounds, the synthesis and characterization of this substance involve various techniques, including NMR spectroscopy, mass spectrometry, and crystallography, to confirm its structure and purity. Further studies may explore its mechanism of action and potential applications in medicinal chemistry.

Formula: C₁₉H₁₂Cl₃N₃OS

InChI: InChI=1S/C19H12Cl3N3OS/c20-14-4-2-13(3-5-14)18-17(25-7-8-27-19(25)24-18)10-23-26-11-12-1-6-15(21)16(22)9-12/h1-10H,11H2

InChI key: InChIKey=ZQWBOKJVVYNKTL-UHFFFAOYSA-N

SMILES: C(=NOCC1=CC(Cl)=C(Cl)C=C1)C2=C(N=C3N2C=CS3)C4=CC=C(Cl)C=C4

Synonyms:

• 6-(4-Chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime
• 6-(4-Chlorophenyl)imidazo[2,1-b]thiazole-5-carboxaldehyde O-[(3,4-dichlorophenyl)methyl]oxime
• Imidazo[2,1-b]thiazole-5-carboxaldehyde, 6-(4-chlorophenyl)-, O-[(3,4-dichlorophenyl)methyl]oxime
• CITCO
• 6-(4-Chlorophenyl)imidazo-[2,1-b]thiazole-5-carbaldehyde-O-(3,4-dichlorobenzyl)oxime

CITCO

CAS: 338404-52-7

CITCO, an imidazothiazole, selectively inhibits BTSCs growth with 49 nM EC50 on PXR and is a CAR agonist.

Formula: C₁₉H₁₂Cl₃N₃OS

Purity: 99.24%

Color and Shape: Solid

Molecular weight: 436.74

Ref: TM-T14973

CITCO

CAS: 338404-52-7

Formula: C₁₉H₁₂Cl₃N₃OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 436.7421

Ref: IN-DA00CNAG

CITCO

CAS: 338404-52-7

Formula: C₁₉H₁₂N₃OCl₃S

Molecular weight: 436.74

Ref: 7W-GL7022

CITCO

CAS: 338404-52-7

CITCO

Purity: ≥98%

Molecular weight: 436.74g/mol

Ref: 54-BUP10379

CITCO

Controlled Product

CAS: 338404-52-7

Applications CITCO is a cell-permeable imidazothiazole compound that acts a CAR agonist.

Formula: C₁₉H₁₂Cl₃N₃OS

Color and Shape: Neat

Molecular weight: 436.74

Ref: TR-C433048