CAS 33868-03-0

1,7-Dimethyluric acid

Description:

1,7-Dimethyluric acid is a purine derivative characterized by the presence of two methyl groups attached to the nitrogen atoms at positions 1 and 7 of the uric acid structure. This compound is a white to off-white solid that is soluble in water and exhibits weak acidic properties due to the presence of carboxylic acid functional groups. Its molecular formula is C₉H₁₁N₅O₃, and it has a molecular weight that reflects its composition of carbon, hydrogen, nitrogen, and oxygen. 1,7-Dimethyluric acid is of interest in biochemical research, particularly in studies related to purine metabolism and its potential implications in various physiological processes. It may also serve as a metabolite in the breakdown of caffeine and other methylxanthines. As with many uric acid derivatives, it is important to consider its role in human health, particularly in relation to conditions such as gout and kidney function. Proper handling and storage conditions are essential due to its biochemical activity.

Formula: C₇H₈N₄O₃

InChI: InChI=1S/C7H8N4O3/c1-10-3-4(8-6(10)13)9-7(14)11(2)5(3)12/h1-2H3,(H,8,13)(H,9,14)

InChI key: InChIKey=NOFNCLGCUJJPKU-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(=O)N2C)NC(=O)N1C

Synonyms:

• 1,7-Dimethyl-1H-purine-2,6,8(3H,7H,9H)-trione
• 1,7-Dimethyl-2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione
• 1,7-Dimethyl-3,9-dihydropurine-2,6,8-trione
• 1,7-dimethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
• 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,7-dimethyl-
• 7,9-Dihydro-1,7-dimethyl-1H-purine-2,6,8(3H)-trione
• Uric acid, 1,7-dimethyl-
• 1,7-Dimethyluric acid

1,7-Dimethyluric acid

CAS: 33868-03-0

Ref: 7W-GW2666

1,7-Dimethyluric Acid

Controlled Product

CAS: 33868-03-0

Applications A metabolite of Caffeine.
References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),

Formula: C₇H₈N₄O₃

Color and Shape: Neat

Molecular weight: 196.16

Ref: TR-D479695

1,7-Dimethyluric acid

Controlled Product

CAS: 33868-03-0

1,7-Dimethyluric acid (1,7-DMUA) is a metabolite of caffeine that is excreted in urine. 1,7-DMUA has been shown to be an analytical marker for the study of drug interactions. 1,7-DMUA has also been found to be a biomarker for obesity and may be a useful tool for the diagnosis of metabolic syndrome.

Formula: C₇H₈N₄O₃

Purity: Min. 95%

Color and Shape: White To Light (Or Pale) Red Solid

Molecular weight: 196.16 g/mol

Ref: 3D-FD22414