CAS 338736-46-2

(4-Methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine hydrochloride

Description:

(4-Methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine hydrochloride, with the CAS number 338736-46-2, is a chemical compound characterized by its complex structure, which includes a phenyl group and a quinazoline moiety. The presence of methoxy groups on both the phenyl and quinazoline rings enhances its solubility and may influence its biological activity. As a hydrochloride salt, it is typically more stable and soluble in aqueous solutions, making it suitable for various pharmaceutical applications. This compound may exhibit properties such as potential anti-cancer or anti-inflammatory activities, as suggested by its structural components, which are often associated with biological activity. Its synthesis involves standard organic chemistry techniques, including amination and methoxylation reactions. The compound's purity and identity can be confirmed through techniques like NMR spectroscopy, mass spectrometry, and HPLC. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information, ensuring proper laboratory practices are followed.

LY 456236

CAS: 338736-46-2

Formula: C₁₆H₁₆ClN₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 317.7701

Ref: IN-DA00C97G

LY 456236 hydrochloride

CAS: 338736-46-2

LY 456236 hydrochloride

Purity: ≥98%

Molecular weight: 317.77g/mol

Ref: 54-BUP11454

LY 456236

Controlled Product

CAS: 338736-46-2

Applications LY 456236 is a mGlu1 receptor antagonists, which may be used in the treatment of chronic pain and epilepsy and other seizure disorders.
References Shannon, H. et al.: Neuropharmacol., 49, 188 (2005); Varty, G. et al.: Psychopharmacol., 179, 207 (2005)

Formula: C₁₆H₁₅N₃O₂·HCl

Color and Shape: Neat

Molecular weight: 317.77

Ref: TR-L486730

LY-456236

CAS: 338736-46-2

LY-456236 is a piperazine compound that inhibits the activity of β-catenin, which is a protein that plays a key role in cell signaling. Inhibiting β-catenin may lead to an improvement in psychotic disorders. LY-456236 has shown to inhibit glutamate release and activity of glutamate receptor subtype NMDARs, which are involved in neuronal function. This drug also inhibits locomotor activity and induces brain infarction in rats, suggesting that it could have potential as a treatment for Parkinson's disease.

Formula: C₁₆H₁₅N₃O₂·HCl

Purity: Min. 95%

Molecular weight: 317.77 g/mol

Ref: 3D-NNA73646

LY 456236 hydrochloride

CAS: 338736-46-2

LY 456236 hydrochloride (MPMQ hydrochloride) is an mGlu1 receptor antagonist with an ic50 value of 143 nM.

Formula: C₁₆H₁₆ClN₃O₂

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 317.77

Ref: TM-T22954